Gilday Sarah E, Schwartz Mark S, Bylski-Austrow Donita I, Glos David L, Schultz Lindsay, O'Hara Sara, Jain Viral V, Sturm Peter F
Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
The Children's Hospital at Saint Francis, Warren Clinic, Tulsa, OK.
J Pediatr Orthop. 2018 Mar;38(3):e133-e137. doi: 10.1097/BPO.0000000000001119.
Magnetically controlled growing rods (MCGRs) are increasingly used in the treatment of early onset scoliosis (EOS). Few studies have reported whether desired lengthening can reliably be achieved, or if prior spine instrumentation and large tissue depths affect lengthening. In this clinical study of EOS patients, it was hypothesized that increases in rod length would equal programmed increases, patients with prior spine instrumentation would lengthen less than patients without prior surgery, and larger tissue depths would decrease lengthening success.
A retrospective chart review was conducted on EOS patients with single and dual MCGRs placed between April 2014 to September 2015 and distracted at a single institution. Rod distraction was measured at each visit using ultrasound. Differences between programmed and actual distraction for each patient, and between groups with and without prior spine instrumentation, were determined by 2-tailed t tests. Regression and correlation were used to determine the relationship between tissue depth and length increases.
Thirty-one patients were included, 18 males, 13 females, age 8.1 (±2.5) years, with major curves measuring 60 (±14.6) degrees at time of MCGR insertion. In the 12 patients with prior instrumentation, time from initial growing rod placement to MCGR insertion was 23.1 (±10.6) months. The number of surgical procedures before MCGR insertion was 2.8 (±2.0). Total length increase relative to the programmed distraction was 86% (±21) (P<0.001). Length increases for patients with and without prior surgery were 87% (±23) and 86% (±19), respectively (P>0.9). Total lengthening was inversely proportional to tissue depth (r=0.38, P<0.01); the decrease in lengthening achieved was 2.1%/mm of tissue depth.
Increases in rod length were 14% lower than the programmed distraction. Prior instrumentation did not impact the amount of rod distraction. Greater distance between the rod and the skin surface negatively affected the magnitude of distraction.
磁控生长棒(MCGRs)越来越多地用于早发性脊柱侧弯(EOS)的治疗。很少有研究报告是否能可靠地实现预期的延长,或者先前的脊柱内固定和较大的组织深度是否会影响延长效果。在这项针对EOS患者的临床研究中,研究假设棒长度的增加将等于设定的增加量,有先前脊柱内固定的患者延长程度将小于没有先前手术的患者,并且较大的组织深度会降低延长成功率。
对2014年4月至2015年9月期间在单一机构置入单根和双根MCGRs并进行撑开的EOS患者进行回顾性病历审查。每次随访时使用超声测量棒的撑开情况。通过双尾t检验确定每位患者设定撑开量与实际撑开量之间的差异,以及有和没有先前脊柱内固定的组之间的差异。使用回归和相关性分析来确定组织深度与长度增加之间的关系。
纳入31例患者,18例男性,13例女性,年龄8.1(±2.5)岁,置入MCGRs时主弯角度为60(±14.6)度。在12例有先前内固定的患者中,从最初生长棒置入到MCGRs置入的时间为23.1(±10.6)个月。MCGRs置入前的手术次数为2.8(±2.0)次。相对于设定撑开量的总长度增加为86%(±21)(P<0.001)。有和没有先前手术的患者长度增加分别为87%(±23)和86%(±19)(P>0.9)。总延长量与组织深度成反比(r=0.38,P<0.01);每增加1mm组织深度,延长量减少2.1%。
棒长度的增加比设定撑开量低14%。先前的内固定不影响棒的撑开量。棒与皮肤表面之间的距离越大,对撑开幅度的负面影响越大。