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癌症患者化疗期间的风险预测与触觉感觉障碍

Risk prediction and impaired tactile sensory perception among cancer patients during chemotherapy.

作者信息

Cardoso Ana Carolina Lima Ramos, Araújo Diego Dias de, Chianca Tânia Couto Machado

机构信息

MSc, Technical Manageress, Hope Oncologia, Coronel Fabriciano, MG, Brazil. Doctoral student, Departamento de Enfermagem Básica, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

PhD, Departamento de Enfermagem Básica, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. Professor, Departamento de Enfermagem, Universidade Estadual de Montes Claros, Montes Claros, MG, Brazil.

出版信息

Rev Lat Am Enfermagem. 2018 Jan 8;25:e2957. doi: 10.1590/1518-8345.1979.2957.

DOI:10.1590/1518-8345.1979.2957
PMID:29319742
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5768208/
Abstract

OBJECTIVES

to estimate the prevalence of impaired tactile sensory perception, identify risk factors, and establish a risk prediction model among adult patients receiving antineoplastic chemotherapy.

METHOD

historical cohort study based on information obtained from the medical files of 127 patients cared for in the cancer unit of a private hospital in a city in Minas Gerais, Brazil. Data were analyzed using descriptive and bivariate statistics, with survival and multivariate analysis by Cox regression.

RESULTS

57% of the 127 patients included in the study developed impaired tactile sensory perception. The independent variables that caused significant impact, together with time elapsed from the beginning of treatment up to the onset of the condition, were: bone, hepatic and regional lymph node metastases; alcoholism; palliative chemotherapy; and discomfort in lower limbs.

CONCLUSION

impaired tactile sensory perception was common among adult patients during chemotherapy, indicating the need to implement interventions designed for early identification and treatment of this condition.

摘要

目的

评估接受抗肿瘤化疗的成年患者中触觉感觉受损的患病率,确定危险因素,并建立风险预测模型。

方法

基于从巴西米纳斯吉拉斯州某城市一家私立医院癌症科护理的127例患者的病历中获取的信息进行历史性队列研究。使用描述性和双变量统计分析数据,并通过Cox回归进行生存和多变量分析。

结果

纳入研究的127例患者中有57%出现触觉感觉受损。造成显著影响的自变量,以及从治疗开始到该病症发作所经过的时间,包括:骨、肝和区域淋巴结转移;酗酒;姑息化疗;以及下肢不适。

结论

触觉感觉受损在化疗期间的成年患者中很常见,这表明需要实施旨在早期识别和治疗这种病症的干预措施。