Rudrappa Mohan, Kokatnur Laxmi, Chernyshev Oleg
Department of Pulmonary and Critical Care, Louisiana State University Health Science Center, Shreveport, LA 71115, USA.
Department of Neurology, Louisiana State University Health Science Center, Shreveport, LA 71115, USA.
Diseases. 2018 Jan 10;6(1):7. doi: 10.3390/diseases6010007.
West Nile virus infection in humans is mostly asymptomatic. Less than 1% of neuro-invasive cases show a fatality rate of around 10%. Acute flaccid paralysis of respiratory muscles leading to respiratory failure is the most common cause of death. Although the peripheral nervous system can be involved, isolated phrenic nerve palsy leading to respiratory failure is rare and described in only two cases in the English literature. We present another case of neurological respiratory failure due to West Nile virus-induced phrenic nerve palsy. Our case reiterates the rare, but lethal, consequences of West Nile virus infection, and the increase of its awareness among physicians.
人类感染西尼罗河病毒大多没有症状。不到1%的神经侵袭性病例显示死亡率约为10%。呼吸肌急性弛缓性麻痹导致呼吸衰竭是最常见的死亡原因。虽然外周神经系统可能受累，但孤立性膈神经麻痹导致呼吸衰竭很罕见，英文文献中仅报道过两例。我们报告另一例因西尼罗河病毒引起膈神经麻痹导致的神经源性呼吸衰竭病例。我们的病例再次强调了西尼罗河病毒感染罕见但致命的后果，以及提高医生对其认识的重要性。
