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本文引用的文献

1
Lower Serum Vitamin D Level Was Associated with Risk of Dry Eye Syndrome.较低的血清维生素D水平与干眼病风险相关。
Med Sci Monit. 2017 May 10;23:2211-2216. doi: 10.12659/msm.901857.
2
Dry Eye Disease Patients with Xerostomia Report Higher Symptom Load and Have Poorer Meibum Expressibility.患有口干症的干眼症患者报告症状负担更高且睑板腺分泌能力更差。
PLoS One. 2016 May 5;11(5):e0155214. doi: 10.1371/journal.pone.0155214. eCollection 2016.
3
Xerostomia among older home care clients.老年居家护理客户的口腔干燥症
Community Dent Oral Epidemiol. 2016 Jun;44(3):232-8. doi: 10.1111/cdoe.12210. Epub 2016 Jan 6.
4
Thyroid associated ophthalmopathy - a review.甲状腺相关性眼病——综述
Malays Fam Physician. 2009 Apr 30;4(1):8-14. eCollection 2009.
5
Is dry eye an environmental disease?干眼症是一种环境性疾病吗?
Arq Bras Oftalmol. 2014 May-Jun;77(3):193-200. doi: 10.5935/0004-2749.20140050.
6
Dry eye syndrome in subjects with diabetes and association with neuropathy.糖尿病患者的干眼综合征及其与神经病变的关联。
Diabetes Care. 2014 Oct;37(10):e210-1. doi: 10.2337/dc14-0860.
7
The effect of antihypertensive therapy on dry eye disease.抗高血压治疗对干眼症的影响。
Cutan Ocul Toxicol. 2015;34(2):117-23. doi: 10.3109/15569527.2014.912660. Epub 2014 Jun 18.
8
Dry eye disease, dry eye symptoms and depression: the Beijing Eye Study.干眼疾病、干眼症状与抑郁:北京眼病研究。
Br J Ophthalmol. 2013 Nov;97(11):1399-403. doi: 10.1136/bjophthalmol-2013-303838. Epub 2013 Sep 7.
9
Do men consult less than women? An analysis of routinely collected UK general practice data.男性就诊次数是否少于女性?基于英国常规收集的全科医疗数据的分析。
BMJ Open. 2013 Aug 19;3(8):e003320. doi: 10.1136/bmjopen-2013-003320.
10
Dry eye disease in French elderly subjects: the Alienor Study.法国老年人群干眼研究:Alienor 研究。
Acta Ophthalmol. 2014 Sep;92(6):e429-36. doi: 10.1111/aos.12174. Epub 2013 Jun 7.

波兰卢布林地区非干燥综合征成年人群的眼部干燥和口干主观投诉。

Subjective Complaints of Ocular Dryness and Xerostomia Among the Non-Sjögren Adult Population of Lublin Region, Poland.

机构信息

Department of Conservative Dentistry and Endodontics, Medical University of Lublin, Lublin, Poland.

Department of Diagnostics and Microsurgery of Glaucoma, Medical University of Lublin, Lublin, Poland.

出版信息

Med Sci Monit. 2018 Jan 10;24:200-206. doi: 10.12659/msm.906618.

DOI:10.12659/msm.906618
PMID:29320472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5771163/
Abstract

BACKGROUND Eye and mouth dryness are the most common symptoms reported during ophthalmological and dental examinations, and their frequency increases with age. In connection with population aging and the huge variety of factors and conditions that can induce this condition, it is becoming a serious and growing problem. The purpose of the present study was to determine whether ocular dryness and concomitant xerostomia is associated with particular systemic diseases. MATERIAL AND METHODS We enrolled 642 non-Sjögren patients referred for examination to the ophthalmology or dental clinic of Lublin region, Poland. The research was conducted using a standardized interview: The Interview and Examination Questionnaire. All patients responded to the survey questions, which concerned systemic diseases, lifestyle, with special emphasis on computer work, spending time in polluted and air-conditioned rooms, and subsequent questions about the subjective symptoms of ocular and mouth dryness. RESULTS There were 424 patients who presented signs and symptoms of both ocular and mouth dryness. Our study showed a statistically significant association between this condition and the age and sex of the patients and systemic diseases such as hypertension (p=0.0000), cardiovascular disease (p=0.057), and stress (p=0.036), and time spent at the computer (p=0.00015). CONCLUSIONS Ocular dryness and concomitant xerostomia may occur in apparently healthy individuals, but is more frequent in patients with systemic disorders. The lack of dry eye and dry mouth symptoms does not exclude insufficient tearing and salivation; thus, the disorders are usually underestimated. Our study indicates that ocular and mouth dryness are the most common conditions seen in out-patients, due to increased use of medications, computers, and air conditioning.

摘要

背景

眼部和口腔干燥是眼科和牙科检查中最常见的症状,且其发生率随年龄增长而增加。随着人口老龄化以及可引起这种情况的各种因素和条件的增加,它正成为一个严重且日益严重的问题。本研究旨在确定眼部干燥和同时发生的口干是否与特定的系统性疾病有关。

材料和方法

我们招募了 642 名非干燥综合征患者,这些患者因眼部或口腔问题到波兰卢布林地区的眼科或牙科诊所就诊。研究使用标准化访谈:访谈和检查问卷进行。所有患者均回答了有关系统性疾病、生活方式的问题,特别强调了计算机工作、在污染和空调房间中度过的时间,以及随后有关眼部和口腔干燥的主观症状的问题。

结果

有 424 名患者表现出眼部和口腔干燥的迹象和症状。我们的研究表明,这种情况与患者的年龄和性别以及高血压(p=0.0000)、心血管疾病(p=0.057)、压力(p=0.036)和使用计算机时间(p=0.00015)等系统性疾病之间存在统计学显著关联。

结论

眼部干燥和同时发生的口干可能发生在看似健康的个体中,但在患有系统性疾病的患者中更为常见。缺乏干眼和口干症状并不排除泪液和唾液分泌不足;因此,这些疾病通常被低估了。我们的研究表明,由于使用药物、计算机和空调的增加,眼部和口腔干燥是门诊患者最常见的疾病。