Belmontesi Magda, De Angelis Francesca, Di Gregorio Carlo, Iozzo Ivano, Romagnoli Marina, Salti Giovanni, Clementoni Matteo Tretti
J Drugs Dermatol. 2018 Jan 1;17(1):83-88.
Hyaluronic acid (HA) is used extensively in aesthetic medicine thanks to its documented role in skin rejuvenation. The specific applications of HA-based products are not always fully acknowledged due to a lack of consistent recommendations. In this paper, the authors have summarized available published data on the range of applications of non-animal stabilized hyaluronic acid (NASHA®) gel skin boosters (NSBs) in several anatomical areas and types of patient, as well as their own recommendations. Overall, the panel agreed that a standard initial protocol treatment of up to 3 sessions, followed by a maintenance schedule, would allow patients to improve and then preserve skin quality over time. Indeed, distinct effects are evident after the first session, but a progressive enhancement of skin texture is detectable for up to 12 months after repeat treatment at 4 to 6 month intervals. Moreover, the authors agreed that the NASHA gel, reaching the dermis, is able to reestablish a greater degree of hydration and stimulate collagen that, in turn, restores the volume and density of the skin. Thus, a strong consensus was reached that NSB procedures are minimally invasive, safe, and effective, and designed to improve skin texture and maintain skin quality.
J Drugs Dermatol. 2018;17(1):83-88.
.透明质酸（HA）因其在皮肤年轻化方面的显著作用而在美容医学中得到广泛应用。由于缺乏一致的建议，基于HA的产品的具体应用并不总是得到充分认可。在本文中，作者总结了已发表的关于非动物稳定化透明质酸（NASHA®）凝胶皮肤增强剂（NSB）在多个解剖区域和患者类型中的应用范围的数据，以及他们自己的建议。总体而言，专家组一致认为，标准的初始治疗方案为最多3次治疗，随后进行维持治疗，这将使患者随着时间的推移改善并保持皮肤质量。事实上，第一次治疗后效果明显，但在每隔4至6个月重复治疗后的12个月内，皮肤质地可逐渐改善。此外，作者一致认为，到达真皮层的NASHA凝胶能够重新建立更高程度的水合作用并刺激胶原蛋白生成，进而恢复皮肤的体积和密度。因此，人们强烈共识NSB程序微创、安全且有效，旨在改善皮肤质地并保持皮肤质量。
《皮肤药物学杂志》。2018年；17(1):83 - 88。
