Fentiman Ian S
Department of Research Oncology, Guy's Hospital, London, England.
Eur J Breast Health. 2018 Jan 1;14(1):5-9. doi: 10.5152/ejbh.2017.3841. eCollection 2018 Jan.
This review examines the symptoms, need for referral and management of the benign breast conditions which afflict males, together with the steps that are necessary to exclude or confirm male breast cancer. The most common complaint is gynaecomastia, either true or pseudo, and the majority of these cases need reassurance without over-investigation. Drugs that induce breast enlargement are described in order that, when possible, a medication switch can be made. Men receiving endocrine therapy for prostate cancer may develop painful gynaecomastia and this can be relieved with tamoxifen. All men with breast cancer need mammography as part of their work-up but this should not be used as a screening technique for symptomatic males. Because of lack of lobular development, both cysts and fibroadenomas are very rare in men; but those with nipple discharge need referral and investigation as some will have underlying malignancy.
本综述探讨了困扰男性的良性乳腺疾病的症状、转诊需求及管理方法,以及排除或确诊男性乳腺癌所需的步骤。最常见的主诉是真性或假性男性乳房发育,这些病例中的大多数只需给予安慰,无需过度检查。文中描述了可导致乳房增大的药物,以便在可能的情况下更换药物。接受前列腺癌内分泌治疗的男性可能会出现疼痛性男性乳房发育,使用他莫昔芬可缓解。所有乳腺癌男性患者在检查过程中均需进行乳房X线摄影,但这不应作为有症状男性的筛查技术。由于男性乳腺小叶发育不足,囊肿和纤维腺瘤在男性中非常罕见;但有乳头溢液的男性需要转诊并接受检查,因为其中一些人可能患有潜在恶性肿瘤。