Pediatric Intensive Care Unit, Arnaud de Villeneuve Hospital, Montpellier University Hospital Center, Montpellier, France.
Department of Bacteriology, Arnaud de Villeneuve Hospital, Montpellier University Hospital Center, Montpellier, France.
Eur J Pediatr. 2018 Mar;177(3):451-459. doi: 10.1007/s00431-017-3082-x. Epub 2018 Jan 10.
Placement of a central venous catheter (CVC) in the brachiocephalic vein (BCV) via the ultrasound (US)-guided supraclavicular approach was recently described in children. We aimed to determine the CVC maintenance-related complications at this site compared to the others (i.e., the femoral, the subclavian, and the jugular). We performed a retrospective data collection of prospectively registered data on CVC in young children hospitalized in a pediatric intensive care unit (PICU) during a 4-year period (May 2011 to May 2015). The primary outcome was a composite of central line-associated bloodstream infection (CLABSI) and deep-vein thrombosis (CLAT) according to the CVC site. Two hundred and twenty-five children, with respective age and weight of 7.1 (1.3-40.1) months and 7.7 (3.6-16) kg, required 257 CVCs, including 147 (57.2%) inserted in the BCV. The risk of the primary outcome was lower in the BCV than in the other sites (5.4 vs 16.4%; OR: 0.29; 95% CI: 0.12-0.70; p = 0.006). CLABSI incidence density rate (2.8 vs 8.96 per 1000 catheter days, p < 0.001) and CLAT incidence rate (2.7 vs 10%, p = 0.016) were also lower at this site.
BCV catheterization via the US-guided supraclavicular approach may decrease CVC maintenance-related complications in children hospitalized in a PICU. What is Known: • Placement of a central venous catheter (CVC) in children is associated with mechanical risks during insertion, and with infectious and thrombotic complications during its maintenance. • Ultrasound (US)-guided supraclavicular catheterization of the brachiocephalic vein (BCV) is feasible in infants and children. What is New: • This observational study suggested that BCV catheterization via the US-guided supraclavicular approach was associated with a lower risk of CVC insertion and maintenance-related complications, compared with the other catheterization sites.
与其他部位(股静脉、锁骨下静脉和颈内静脉)相比,确定经超声(US)引导锁骨上途径在头臂静脉(BCV)置入中心静脉导管(CVC)的相关并发症。
我们对 4 年内(2011 年 5 月至 2015 年 5 月)入住儿科重症监护病房(PICU)的小儿前瞻性登记的 CVC 数据进行回顾性数据收集。主要结局是根据 CVC 部位发生导管相关性血流感染(CLABSI)和深静脉血栓形成(CLAT)的复合事件。
225 例年龄 7.1(1.3-40.1)个月、体重 7.7(3.6-16)kg 的患儿需要 257 根 CVC,其中 147 根(57.2%)置入 BCV。BCV 部位的主要结局风险低于其他部位(5.4%比 16.4%;OR:0.29;95%CI:0.12-0.70;p=0.006)。该部位的 CLABSI 发生率密度(2.8 比 8.96/1000 导管日,p<0.001)和 CLAT 发生率(2.7%比 10%,p=0.016)也较低。
经 US 引导锁骨上途径行 BCV 置管可能会降低 PICU 住院患儿的 CVC 维护相关并发症。