Laboratório de Ensaios Farmacológicos e Toxicológicos - LEFT, Instituto de Ciências Biológicas, Universidade Federal do Rio Grande do Sul - FURG, Av. Itália, km 8, Campus Carreiros, Rio Grande, RS, 96203-900, Brazil.
Programa de Pós Graduação em Ciências da Saúde, Universidade Federal do Rio Grande (FURG), Rua Visconde de Paranaguá 102 Centro, Rio Grande, RS, 96203-900, Brazil.
Environ Sci Pollut Res Int. 2018 Mar;25(9):8669-8675. doi: 10.1007/s11356-018-1229-6. Epub 2018 Jan 10.
In this study, hematological and behavioral changes in Wistar rats exposed to soil collected from urban areas next to an industrial complex were investigated. Animals were exposed to soil samples placed at the bottom of cages for 4 days. After this period, behavioral parameters were measured by the open field test and the elevated plus-maze. Blood was collected to measure hematological parameters. The soil from the vicinity of the oil refining industry caused changes in hematological parameters and altered behavioral parameters in both tests. The soil from the vicinity of the petroleum refining industry and fertilizer industries increased the density of white blood cells and decreased exploratory activity in the exposed animals. The results demonstrate that contact with contaminated soils, even for short periods, can cause physiological damage in organisms and that special attention should be given to people who live under constant exposure to these soils.
本研究旨在探讨接触紧邻工业区的城市土壤对 Wistar 大鼠血液学和行为的影响。将土壤样本置于动物笼底，动物暴露于土壤 4 天。暴露期结束后，通过旷场实验和高架十字迷宫实验检测动物的行为参数，采集血液检测血液学参数。炼油工业附近的土壤会引起血液学参数改变，并影响两种实验中的行为参数。石油炼制和化肥工业附近的土壤会增加白细胞密度，减少暴露动物的探索活动。结果表明，即使短时间接触污染土壤也会对生物造成生理损害，因此应特别关注长期接触这些土壤的人群。
