迷迭香、蓖麻油和蜂胶提取物：抗白色念珠菌活性及对牙用丙烯酸树脂性能的影响。
Rosemary, Castor Oils, and Propolis Extract: Activity Against Candida Albicans and Alterations on Properties of Dental Acrylic Resins.
机构信息
Postgraduate Program in Medicine, Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Department of Microbiology, Immunology and Parasitology, ICBS, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
出版信息
J Prosthodont. 2019 Feb;28(2):e863-e868. doi: 10.1111/jopr.12746. Epub 2018 Jan 11.
PURPOSE
To evaluate the in vitro activity of 8% rosemary, 2% castor oils, and 12% propolis glycolic extract against Candida albicans, as well as the physical changes of properties in colorless and pink acrylic resins after immersion in these liquids.
MATERIALS AND METHODS
Colorimetric, roughness, and Knoop microhardness assays were evaluated in 25 specimens distributed into five groups (3 test groups and 2 control groups - distilled water and hypochlorite 1%), totaling five specimens per group for each acrylic resin (colorless and pink). The specimens were individually immersed for 30 minutes in 10 mL of these liquids, washed, and dried once a week. They were maintained in distilled water at 37°C between processes during all experiments. The analyses were performed before immersion and in the 4th and/or 12th month. In vitro, 18 acrylic resins were exposed to C. albicans and, after a process of 30 minutes in immersion in the five groups cited and oil vehicle control of vesicle (liquid Vaseline), the specimens were washed and incubated for 24 hours in 37°C. The growth was determined by colony counting. For comparisons between the groups in each trial and the disinfection test, paired Student's t-tests and ANOVA with post hoc Tukey were performed by the SPSS program, considering α = 0.05.
RESULTS
None of the liquids altered the microhardness, but all the natural compounds and 1% sodium hypochlorite (control) altered color and roughness after the 12th month of immersion in these agents. In the colorless specimens, 8% rosemary oil caused a color change similar to water, and less color and roughness alterations when compared to 2% castor oil and 1% sodium hypochlorite, respectively. There was no growth of yeast colonies after immersion in rosemary oil, propolis glycolic extract, and 1% sodium hypochlorite.
CONCLUSION
Eight percent rosemary oil has the potential to be used as an acrylic resin disinfectant.
目的
评估 8%迷迭香油、2%蓖麻油和 12%蜂胶醇提物对白色念珠菌的体外活性，以及这些液体浸泡后无色和粉红色丙烯酸树脂的颜色和物理性能变化。
材料和方法
在 25 个样本中评估比色、粗糙度和努氏硬度试验，样本分为 5 组（3 个实验组和 2 个对照组-蒸馏水和次氯酸钠 1%），每组 5 个样本，用于两种丙烯酸树脂（无色和粉红色）。将标本单独浸入 10ml 这些液体中 30 分钟，然后清洗并每周干燥一次。所有实验过程中，标本均保存在 37°C 的蒸馏水中。分析在浸泡前和第 4 个月和/或第 12 个月进行。在体外，18 个丙烯酸树脂暴露于白色念珠菌，在浸泡在上述 5 组和油载体对照（液体凡士林）30 分钟后，将标本清洗并在 37°C 孵育 24 小时。通过菌落计数确定生长情况。对于每个试验组和消毒试验组之间的比较，使用 SPSS 程序进行配对学生 t 检验和方差分析，并用 Tukey 事后检验进行比较，α=0.05。
结果
没有一种液体改变了硬度，但所有的天然化合物和 1%次氯酸钠（对照组）在浸泡在这些制剂 12 个月后改变了颜色和粗糙度。在无色标本中，8%迷迭香油引起的颜色变化类似于水，与 2%蓖麻油和 1%次氯酸钠相比，颜色和粗糙度变化较小。迷迭香油、蜂胶醇提物和 1%次氯酸钠浸泡后，酵母菌落无生长。
结论
8%迷迭香油有可能用作丙烯酸树脂消毒剂。
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