Radu Casandra-Maria, Radu Carmen Corina, Bochiș Sergiu-Alin, Arbănași Emil Marian, Lucan Alexandra Ioana, Murvai Viorela Romina, Zaha Dana Carmen
Doctoral School of Biological and Biomedical Sciences, University of Oradea, 1 University Street, 410087 Oradea, Romania.
Department of Forensic Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540139 Targu Mures, Romania.
Pharmacy (Basel). 2023 Feb 10;11(1):33. doi: 10.3390/pharmacy11010033.
The extensive use of antibiotics has resulted in the development of drug-resistant bacteria, leading to a decline in the efficacy of traditional antibiotic treatments. Essential oils (EOs) are phytopharmaceuticals, or plant-derived compounds, that possess beneficial properties such as anti-inflammatory, antibacterial, antimicrobial, antiviral, bacteriostatic, and bactericidal effects. In this review, we present scientific findings on the activity of EOs as an alternative therapy for common oral diseases. This narrative review provides a deeper understanding of the medicinal properties of EOs and their application in dentistry. It not only evaluates the effectiveness of these oils as antibacterial agents against common oral bacteria but also covers general information such as composition, methods of extraction, and potential toxicity. Further nonclinical and clinical studies must be conducted to determine their potential use and safety for treating oral diseases.
抗生素的广泛使用导致了耐药细菌的产生，致使传统抗生素治疗的疗效下降。精油是植物药物，即植物衍生化合物，具有抗炎、抗菌、抗微生物、抗病毒、抑菌和杀菌等有益特性。在本综述中，我们展示了关于精油作为常见口腔疾病替代疗法活性的科学发现。这篇叙述性综述深入探讨了精油的药用特性及其在牙科中的应用。它不仅评估了这些精油作为抗菌剂对抗常见口腔细菌的有效性，还涵盖了诸如成分、提取方法和潜在毒性等一般信息。必须进行进一步的非临床和临床研究，以确定它们在治疗口腔疾病方面的潜在用途和安全性。
