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Max-Bergmann award lecture:A RaPID way to discover bioactive nonstandard peptides assisted by the flexizyme and FIT systems.

作者信息

Suga Hiroaki

机构信息

Department of Chemistry, Graduate School of Science, Tokyo, The University of Tokyo, Japan.

JST-CREST, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.

出版信息

J Pept Sci. 2018 Jan;24(1). doi: 10.1002/psc.3055.

DOI:10.1002/psc.3055
PMID:29322648
Abstract

Although general review articles should cover various people's achievements related to the subject, this review is privileged to describe the technology developed by Suga (and colleagues) as a recipient of the Max-Bergmann Medal in 2016. The technology consists of 3 unique and essential tools, flexizymes, FIT, and RaPID systems. This review describes the history of the development of each tool and discusses the recent applications of the RaPID system to discover potent nonstandard peptides for therapeutic and diagnostic uses.

摘要

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J Pept Sci. 2018 Jan;24(1). doi: 10.1002/psc.3055.
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