Al-Hamoudi Nawwaf, Abduljabbar Tariq, Mirza Sana, Al-Sowygh Zeyad H, Vohra Fahim, Javed Fawad, Akram Zohaib
Department of Periodontics and Community Dentistry, King Saud University, Riyadh, Saudi Arabia.
Department of Prosthetic Dental Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
J Investig Clin Dent. 2018 May;9(2):e12314. doi: 10.1111/jicd.12314. Epub 2018 Jan 10.
The aim of the present study was to assess the effect of scaling and root planing (SRP) on periodontal parameters and whole salivary resistin and interleukin (IL)-6 levels in chronic periodontitis (CP) patients with and without obesity.
Participants were divided into two groups; group 1 included obese and non-obese individuals with CP; and group 2 included obese and non-obese individuals without CP. In both groups, bleeding on probing (BOP) and probing depth (PD) ≥4 mm and whole salivary resistin and IL-6 levels were measured using enzyme-linked immunosorbent assay at baseline and 6 months after SRP. The number of missing teeth was counted, and marginal bone loss was measured on digital panoramic radiographs at baseline and 6 months' postoperatively.
BOP was significantly higher among obese patients in group 1 than obese (P < .001) and non-obese (P < .001) individuals in group 2. At 6 months' follow up, BOP (P < .001) and PD ≥4 mm (P < .001) were significantly lower among obese and non-obese patients in group 1 than their respective baseline values. At 6 months' follow up, BOP (P < .001) and PD ≥4 mm (P < .001) were significantly higher among obese and non-obese individuals in group 1 compared with individuals in group 2.
SRP is effective in reducing periodontal inflammation in CP patients with and without obesity. CP seems to be the primary factor that influences periodontal status and the expression of resistin and IL-6 levels in obese and non-obese patients.
本研究旨在评估龈上洁治和根面平整（SRP）对伴有和不伴有肥胖的慢性牙周炎（CP）患者牙周参数以及全唾液抵抗素和白细胞介素（IL）-6水平的影响。
参与者被分为两组；第1组包括患有CP的肥胖和非肥胖个体；第2组包括未患CP的肥胖和非肥胖个体。在两组中，使用酶联免疫吸附测定法在基线时以及SRP后6个月测量探诊出血（BOP）、探诊深度（PD）≥4mm以及全唾液抵抗素和IL-6水平。记录缺失牙数量，并在基线时和术后6个月通过数字化全景X线片测量边缘骨丧失。
第1组肥胖患者的BOP显著高于第2组肥胖（P <.001）和非肥胖（P <.001）个体。在6个月随访时，第1组肥胖和非肥胖患者的BOP（P <.001）和PD≥4mm（P <.001）显著低于其各自的基线值。在6个月随访时，第1组肥胖和非肥胖个体的BOP（P <.001）和PD≥4mm（P <.001）显著高于第2组个体。
SRP对伴有和不伴有肥胖的CP患者减轻牙周炎症有效。CP似乎是影响肥胖和非肥胖患者牙周状况以及抵抗素和IL-6水平表达的主要因素。
