Morton N E, Berg K, Dahlen G, Ferrell R E, Rhoads G G
Genet Epidemiol. 1985;2(2):113-21. doi: 10.1002/gepi.1370020202.
Segregation analysis of four Lp assays on 557 children in 227 families reveals a dominant major gene and a residual heritable component that may reflect one or more alleles of weaker effect. Close or moderate linkage to esterase-D (ESD) is excluded.
对来自227个家庭的557名儿童进行的四种脂蛋白(Lp)检测的分离分析显示,存在一个显性主基因和一个残余遗传成分,该残余遗传成分可能反映一个或多个效应较弱的等位基因。排除了与酯酶-D(ESD)的紧密或中度连锁关系。