Weitkamp L R, Guttormsen S A, Schultz J S
Department of Psychiatry, University of Rochester School of Medicine and Dentistry, NY 14642.
Hum Genet. 1988 May;79(1):80-2. doi: 10.1007/BF00291716.
A locus, LP, that determines quantitative variation of Lp(a) lipoprotein phenotypes is linked to the plasminogen (PLG) locus (peak lod score = 12.73). This linkage relationship assigns a locus with alleles that have an affect on risk for coronary artery disease to the long arm of chromosome 6.
一个决定Lp(a)脂蛋白表型数量变异的基因座LP与纤溶酶原(PLG)基因座连锁(最高对数优势分数=12.73)。这种连锁关系将一个带有对冠状动脉疾病风险有影响的等位基因的基因座定位于6号染色体长臂。