Dye Alyssa M, Nelson Grace B, Diaz-Thomas Alicia
Pediatr Ann. 2018 Jan 1;47(1):e16-e22. doi: 10.3928/19382359-20171215-01.
Delayed puberty is defined as the absence of physical signs of puberty 2 to 2.5 standard deviations above the mean age and affects approximately 2% of adolescents. Causes of delayed puberty are broadly divided into two categories: hypergonadotropic hypogonadism and hypogonadotropic hypogonadism. One exception to this classification system is constitutional delay of growth and puberty, the most common cause of delayed puberty. For the general pediatrician, knowledge of the different causes and initial steps to evaluation is crucial when a patient with delayed puberty presents. [Pediatr Ann. 2018;47(1):e16-e22.].
青春期延迟被定义为青春期体征缺失,其年龄比平均年龄高出2至2.5个标准差,约2%的青少年受此影响。青春期延迟的原因大致分为两类:高促性腺激素性性腺功能减退和低促性腺激素性性腺功能减退。该分类系统的一个例外是体质性生长和青春期延迟,这是青春期延迟最常见的原因。对于普通儿科医生而言,当遇到青春期延迟的患者时,了解不同病因及初始评估步骤至关重要。[《儿科年鉴》。2018年;47(1):e16 - e22。]