Michael Smith Laboratories, University of British Columbia, 2185 East Mall, Vancouver, BC, Canada; Department of Microbiology & Immunology, University of British Columbia, Vancouver, BC, Canada.
Michael Smith Laboratories, University of British Columbia, 2185 East Mall, Vancouver, BC, Canada; Department of Biochemistry & Molecular Biology, University of British Columbia, Vancouver, BC, Canada.
Cell Host Microbe. 2018 Jan 10;23(1):10-13. doi: 10.1016/j.chom.2017.12.008.
Our expanding knowledge of microbial mechanisms is challenging the notion of "good" versus "bad" microbes and encouraging a better understanding of their roles in various contexts before their widespread therapeutic and clinical application. The intestinal microbe Akkermansia muciniphila, a promising probiotic with an emerging cautionary tale, best highlights this challenge.
我们对微生物机制的不断深入了解，正在挑战“有益”和“有害”微生物的概念，并鼓励在广泛的治疗和临床应用之前，更好地了解它们在各种环境下的作用。肠道微生物 Akkermansia muciniphila 是一种很有前途的益生菌，但也有一个值得警惕的故事，它很好地突出了这一挑战。
