Travi Bruno L, Cordeiro-da-Silva Anabela, Dantas-Torres Filipe, Miró Guadalupe
Department of Internal Medicine-Division of Infectious Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America.
Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
PLoS Negl Trop Dis. 2018 Jan 11;12(1):e0006082. doi: 10.1371/journal.pntd.0006082. eCollection 2018 Jan.
This article reviews essential topics of canine visceral leishmaniasis (CVL) due to Leishmania infantum infection. It focuses on the current serological and molecular diagnostic methods used in epidemiological research and veterinary clinics to diagnose CVL and includes new point-of-care (POC) tests under development. The efficacy of different treatment regimens on the clinical improvement and infectiousness of dogs is also addressed. In the last section, the review provides a critical appraisal of the effectiveness of different control measures that have been implemented to curb disease transmission.
本文综述了由婴儿利什曼原虫感染引起的犬内脏利什曼病（CVL）的重要主题。它重点关注目前在流行病学研究和兽医临床中用于诊断CVL的血清学和分子诊断方法，并包括正在开发的新型即时检测（POC）。还讨论了不同治疗方案对犬临床改善和传染性的疗效。在最后一部分，该综述对为遏制疾病传播而实施的不同控制措施的有效性进行了批判性评估。
