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Insights and barriers to clinical use of serotonin transporter pharmacogenetics in antidepressant therapy.

作者信息

Stevenson James M

机构信息

Department of Pharmacy & Therapeutics, University of Pittsburgh, School of Pharmacy, 335 Sutherland Drive, 209 Salk Pavilion, Pittsburgh, PA 15261, USA.

出版信息

Pharmacogenomics. 2018 Feb;19(3):167-170. doi: 10.2217/pgs-2017-0196. Epub 2018 Jan 12.

DOI:10.2217/pgs-2017-0196
PMID:29325499
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6291898/
Abstract
摘要

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本文引用的文献

1
Antidepressant Use Among Persons Aged 12 and Over:United States,2011-2014.12岁及以上人群的抗抑郁药使用情况:美国,2011 - 2014年
NCHS Data Brief. 2017 Aug(283):1-8.
2
Effect of Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control Among Patients Undergoing Hip or Knee Arthroplasty: The GIFT Randomized Clinical Trial.基因型指导的华法林剂量调整对髋或膝关节置换术患者临床事件及抗凝控制的影响:GIFT随机临床试验
JAMA. 2017 Sep 26;318(12):1115-1124. doi: 10.1001/jama.2017.11469.
3
Serotonin Transporter Gene Polymorphisms and Selective Serotonin Reuptake Inhibitor Tolerability: Review of Pharmacogenetic Evidence.5-羟色胺转运体基因多态性与选择性 5-羟色胺再摄取抑制剂耐受性:药物遗传学证据的综述。
Pharmacotherapy. 2017 Sep;37(9):1089-1104. doi: 10.1002/phar.1978. Epub 2017 Aug 11.
4
Looking Beyond the 5-HTTLPR Polymorphism: Genetic and Epigenetic Layers of Regulation Affecting the Serotonin Transporter Gene Expression.超越 5-HTTLPR 多态性:影响血清素转运体基因表达的遗传和表观遗传调控层。
Mol Neurobiol. 2017 Dec;54(10):8386-8403. doi: 10.1007/s12035-016-0304-6. Epub 2016 Dec 8.
5
Role of the 5-HTTLPR and SNP Promoter Polymorphisms on Serotonin Transporter Gene Expression: a Closer Look at Genetic Architecture and In Vitro Functional Studies of Common and Uncommon Allelic Variants.5-HTTLPR 和 SNP 启动子多态性对 5-羟色胺转运体基因表达的作用:常见和罕见等位基因变异的遗传结构和体外功能研究的深入探讨。
Mol Neurobiol. 2016 Oct;53(8):5510-26. doi: 10.1007/s12035-015-9409-6. Epub 2015 Oct 13.
6
Measurement errors in polymerase chain reaction are a confounding factor for a correct interpretation of 5-HTTLPR polymorphism effects on lifelong premature ejaculation: a critical analysis of a previously published meta-analysis of six studies.聚合酶链反应中的测量误差是正确解读5-羟色胺转运体基因启动子区域多态性(5-HTTLPR)对终身性早泄影响的一个混杂因素:对先前发表的六项研究的荟萃分析的批判性分析
PLoS One. 2014 Mar 3;9(3):e88031. doi: 10.1371/journal.pone.0088031. eCollection 2014.
7
Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy.基于 5-羟色胺转运体基因启动子多态性(5-HTTLPR)与抗抑郁疗效关联的荟萃分析
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8
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Depress Anxiety. 2010 Mar;27(3):260-9. doi: 10.1002/da.20660.
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Moderation of antidepressant response by the serotonin transporter gene.血清素转运体基因对抗抑郁反应的调节作用。
Br J Psychiatry. 2009 Jul;195(1):30-8. doi: 10.1192/bjp.bp.108.062521.
10
The association of serotonin transporter genotypes and selective serotonin reuptake inhibitor (SSRI)-associated sexual side effects: possible relationship to oral contraceptives.血清素转运体基因分型与选择性血清素再摄取抑制剂(SSRI)相关的性功能副作用的关联:与口服避孕药的可能关系。
Hum Psychopharmacol. 2009 Apr;24(3):207-15. doi: 10.1002/hup.1006.