Goodwin J S
Med Clin North Am. 1985 Jul;69(4):793-804. doi: 10.1016/s0025-7125(16)31019-7.
The author discusses the evidence that PGE is an immunomodulator and addresses the thesis that nonsteroidal anti-inflammatory agents, by blocking endogenous PGE production, act to partially correct the immunologic aberrations involved in the pathogenesis of rheumatoid arthritis.
作者讨论了前列腺素E(PGE)作为一种免疫调节剂的证据,并论述了非甾体抗炎药通过阻断内源性PGE生成,从而部分纠正类风湿关节炎发病机制中涉及的免疫异常这一论点。