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以轻微症状表现的严重低钠血症

Severe Hyponatremia Presenting with Minimal Symptoms.

作者信息

Lwanga Anita, Mohamed Amira, Patel Mayank, Serrano Andres

机构信息

Department of Academic Internal Medicine and Geriatrics, University of Illinois at Chicago.

Department of Critical Care, Icahn School of Medicine at Mount Sinai.

出版信息

Cureus. 2017 Nov 8;9(11):e1830. doi: 10.7759/cureus.1830.

Abstract

Hyponatremia is a common electrolyte abnormality, however, encountering a patient with serum sodium level below 100 mEq/L and minimal symptoms is unusual. We present the case of an 86-year-old woman who was found to have serum sodium levels of 99 mEq/L. Her only complaint was difficulty in walking. On admission, and throughout her hospital stay, she did not have altered mental status, focal neurological deficits, or adverse outcomes. Her history, blood work, and urine studies pointed towards a diagnosis of thiazide-associated hyponatremia. Thiazide-associated hyponatremia can occur at any time during the course of thiazide administration. The first step that should be taken to manage this condition is discontinuing the medication. The lesson learned from this case is that the degree of hyponatremia does not always correlate with the severity of symptoms.

摘要

低钠血症是一种常见的电解质异常,但遇到血清钠水平低于100 mEq/L且症状轻微的患者并不常见。我们报告一例86岁女性患者,其血清钠水平为99 mEq/L。她唯一的主诉是行走困难。入院时及住院期间,她没有精神状态改变、局灶性神经功能缺损或不良后果。她的病史、血液检查和尿液检查提示诊断为噻嗪类药物相关低钠血症。噻嗪类药物相关低钠血症可在噻嗪类药物给药过程中的任何时间发生。处理这种情况的第一步是停用该药物。从这个病例中学到的经验是,低钠血症的程度并不总是与症状的严重程度相关。

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本文引用的文献

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Differential diagnosis of hyponatraemia.低钠血症的鉴别诊断。
Best Pract Res Clin Endocrinol Metab. 2012 Mar;26 Suppl 1:S7-15. doi: 10.1016/S1521-690X(12)70003-9.

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