Ayhan Ziya, Kaya Sureyya Yigit, Ozcan Mehmet Ali, Saatci Ali Osman
Department of Ophthalmology, Dokuz Eylul University School of Medicine, Izmir, Turkey.
Department of Haematology-Oncology, Dokuz Eylul University School of Medicine, Izmir, Turkey.
GMS Ophthalmol Cases. 2017 Dec 15;7:Doc29. doi: 10.3205/oc000080. eCollection 2017.
We describe a 36-year-old woman with a relapsing Hodgkin's lymphoma who developed a severe bilateral sudden visual loss almost three weeks after the initiation of brentuximab therapy. Ancillary fundus tests yielded bilateral severe retinal arteriolar occlusion 360° and serous macular retinal detachment. No visual improvement could be achieved despite the pulse corticosteroid therapy and a single bilateral intravitreal aflibercept administration cessation of the brentuximab therapy. Unfortunately, she succumbed to respiratory failure almost six weeks after the diagnosis of Purtscher-like retinopathy.
我们描述了一名36岁复发性霍奇金淋巴瘤女性患者，在开始使用brentuximab治疗近三周后出现严重的双侧突发性视力丧失。辅助眼底检查发现双侧360°严重视网膜小动脉闭塞和浆液性黄斑视网膜脱离。尽管进行了脉冲皮质类固醇治疗以及单次双侧玻璃体内注射阿柏西普，并停用了brentuximab治疗，但视力仍未改善。不幸的是，在诊断为普-罗二氏样视网膜病变近六周后，她死于呼吸衰竭。
