Kovach Jaclyn L
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
Retin Cases Brief Rep. 2018;12(3):240-241. doi: 10.1097/ICB.0000000000000471.
To report a case of Purtscher-like retinopathy associated with gemcitabine.
The author reports a 68-year-old woman who presented with a 4-month history of bilateral vision loss. She had a history of diabetes, hypertension, and leiomyosarcoma, diagnosed 5 months before presentation and had completed 5 cycles of combination treatment with gemcitabine and docetaxel. Clinical examination revealed a Purtscher-like retinopathy that improved after gemcitabine cessation without the development of cystoid macular edema or retinal neovascularization.
This case highlights the importance of recognizing gemcitabine-induced ischemic retinopathy that can be associated with life-threatening myocardial or renal ischemia.
报告1例与吉西他滨相关的类Purtscher样视网膜病变。
作者报告了1例68岁女性，有4个月的双侧视力丧失病史。她有糖尿病、高血压和平滑肌肉瘤病史，在就诊前5个月被诊断出，并且已经完成了5个周期的吉西他滨与多西他赛联合治疗。临床检查发现类Purtscher样视网膜病变，在停用吉西他滨后病情改善，未出现黄斑囊样水肿或视网膜新生血管形成。
该病例突出了认识吉西他滨诱导的缺血性视网膜病变的重要性，这种病变可能与危及生命的心肌或肾脏缺血有关。
