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肺部空洞性病变疑似恶性,结果显示…… (原文句子不完整,翻译可能不太准确,建议提供完整原文)

Cavitary lung lesion suspicious for malignancy reveals .

作者信息

Fogla Sumit, Pansare Vaishali M, Camero Luis G, Syeda Uzma, Patil Naveen, Chaudhury Arun

机构信息

Beaumont Hospital, Grosse Pointe, MI, USA.

Arkansas Department of Health, Little Rock, USA.

出版信息

Respir Med Case Rep. 2018 Jan 3;23:83-85. doi: 10.1016/j.rmcr.2017.12.011. eCollection 2018.

Abstract

We report the case of a 68-year-old gentleman who presented with musculoskeletal chest pain which appeared suddenly when he bent over with his dog. The chest pain was localized to the left lower chest and increased with movement and deep breathing. The patient did not complain weight loss, night sweat, fever or chill. He complained of mild cough, with expectoration of whitish mucus. Imaging revealed cavitary chest lesion in the right upper lobe, which was initially suspected to be lung cancer. The patient had a 50-year-old history of smoking 2 packs per day. PET CT imaging did not reveal any specific activity. Needle biopsy and bronchoalveolar lavage, however, did not reveal any malignant cells. Rather, necrotic tissues were observed. A wedge resection of the lung mass was performed. No common organisms or fungi could be grown. However, acid fast bacilli were observed in clumps. The morphology hinted towards non-tuberculous mycobacterial organism(s). Molecular studies revealed infection with . The patient was started on an anti-tuberculous regimen of INH, rifampicin, ethambutol and PZA, with pyridoxine. The patient is a Vietnam veteran and complained of exposure to dust from a bird's nest and asbestos exposure in childhood, but no specific exposure to tuberculosis. The patient had an uneventful recovery post-surgery. He complained of some nausea after initiation of the antituberculous medications, but his pain subsided with time. The patient had diabetes, though specific reasons of compromise of immune status could not be pinpointed as causative of his nontuberculous mycobacterial lung infection.

摘要

我们报告了一例68岁男性患者的病例,该患者在弯腰逗狗时突然出现肌肉骨骼性胸痛。胸痛局限于左下胸部,活动和深呼吸时加重。患者无体重减轻、盗汗、发热或寒战主诉。他诉有轻度咳嗽,咳出白色黏液。影像学检查显示右上叶有空洞性胸部病变,最初怀疑为肺癌。该患者有50年吸烟史,每天2包。PET CT成像未显示任何特异性活性。然而,经皮肺穿刺活检和支气管肺泡灌洗未发现任何恶性细胞,而是观察到坏死组织。对肺部肿块进行了楔形切除术。未培养出常见微生物或真菌,但观察到成团的抗酸杆菌。其形态提示为非结核分枝杆菌。分子研究显示感染了……。患者开始接受异烟肼、利福平、乙胺丁醇和吡嗪酰胺的抗结核治疗方案,并加用吡哆醇。该患者是一名越战退伍军人,诉童年时有鸟巢灰尘暴露和石棉暴露史,但无特定结核暴露史。患者术后恢复顺利。开始抗结核药物治疗后他诉有一些恶心,但疼痛随时间逐渐缓解。患者患有糖尿病,尽管免疫状态受损的确切原因无法确定为其非结核分枝杆菌肺部感染的病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/125b/5760466/fdafc136b801/gr1.jpg

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