Agbenyefia Priscilla, Shilliam Lance A, Stoicea Nicoleta, Roth Andrew, Moran Kenneth R
Department of Anesthesiology, OSU Wexner Medical Center, Columbus, OH, United States.
Department of Anesthesiology, Akron General Medical Center, Akron, OH, United States.
Front Med (Lausanne). 2017 Dec 18;4:222. doi: 10.3389/fmed.2017.00222. eCollection 2017.
Cold urticaria consists of an allergic immune response to cold temperatures with symptoms ranging from pruritic wheals to life-threatening angioedema, bronchospasm, or anaphylactic shock. Adequate planning to maintain normothermia perioperatively is vital due to impaired hypothalamic thermoregulation and overall depression of sympathetic outflow during deep sedation and general anesthesia. This case report describes the successful perioperative management of a 45-year-old female with a history of cold urticaria undergoing a laparoscopic Nissen fundoplication for refractory gastroesophageal reflux disease and discusses how to appropriately optimize the care of these patients.
寒冷性荨麻疹是对低温的一种过敏性免疫反应，症状从瘙痒性风团到危及生命的血管性水肿、支气管痉挛或过敏性休克不等。由于在深度镇静和全身麻醉期间下丘脑体温调节受损以及交感神经输出总体抑制，围手术期维持正常体温的充分计划至关重要。本病例报告描述了一名有寒冷性荨麻疹病史的45岁女性，因难治性胃食管反流病接受腹腔镜尼森胃底折叠术的围手术期成功管理，并讨论了如何适当优化这些患者的护理。
