Bojanowska-Poźniak Katarzyna, Nurkowska Monika, Danilewicz Marian, Pietruszewska Wioletta
Department of Otorhinolaryngology, Medical University of Lodz, Poland.
Department of Pathomorphology, Medical University of Lodz, Poland; Head of the Clinic prof. Marian Danilewicz Phd, MD.
Otolaryngol Pol. 2017 Dec 30;71(6):14-21. doi: 10.5604/01.3001.0010.7192.
Malignant lymphoma (ML) is a neoplasm caused by clonal expansion of undifferentiated B, T and NK-lymphoid cells. WHO classification divides lymphomas into two main types, i.e. Hodgkin lymphoma (HL), and non-Hodgkin lymphoma (NHL), with numerous subtypes. The majority of MLs are localized in lymph nodes, but extranodal locations are also possible. MLs represent approximately 3-5% of all malignant neoplasms in Poland, but their incidence has been increasing in recent years, especially in young patients. The objective of the study was to evaluate clinical manifestations and diagnostic process in patients with malignant lymphomas of the head and neck region as diagnosed in the Department of Otorhinolaryngology of the Medical University of Lodz in years 2013-2017.
30 patients diagnosed with malignant lymphomas of the head and neck region at the Departbadament of Otorhinolaryngology of the Medical University of Lodz in 2013-2017.
The study group consisted of 8 cases of nodal lymphomas and 22 cases of extranodal lymphomas. In 29 cases B-cell lymphomas were diagnosed. The most common symptoms included lymphadenopathy or neck tumor. Other symptoms were associated with the location of tumors in particular body organs. The diagnosis was based on histopathological examination of biopsy (needle or surgical) samples.
Malignant lymphomas should be taken into account during differential diagnosis of the tumor or lymphadenopathy of the neck. The diagnosis is difficult because of the nonspecificity of symptoms and the need for interdisciplinary cooperation of many specialists.
恶性淋巴瘤（ML）是一种由未分化的B、T和NK淋巴细胞克隆性增殖引起的肿瘤。世界卫生组织（WHO）分类将淋巴瘤分为两种主要类型，即霍奇金淋巴瘤（HL）和非霍奇金淋巴瘤（NHL），还有许多亚型。大多数ML局限于淋巴结，但也可能发生在结外部位。在波兰，ML约占所有恶性肿瘤的3%-5%，但近年来其发病率一直在上升，尤其是在年轻患者中。本研究的目的是评估2013年至2017年在罗兹医科大学耳鼻喉科诊断的头颈部恶性淋巴瘤患者的临床表现和诊断过程。
2013年至2017年在罗兹医科大学耳鼻喉科诊断为头颈部恶性淋巴瘤的30例患者。
研究组包括8例淋巴结淋巴瘤和22例结外淋巴瘤。29例诊断为B细胞淋巴瘤。最常见的症状包括淋巴结病或颈部肿块。其他症状与肿瘤在特定身体器官的位置有关。诊断基于活检（针吸或手术）样本的组织病理学检查。
在颈部肿瘤或淋巴结病的鉴别诊断中应考虑恶性淋巴瘤。由于症状的非特异性以及需要许多专家的跨学科合作，诊断较为困难。
