McIlroy M B, Targett R C, Roussin A, Seitz W S
Ultrasound Med Biol. 1985 Sep-Oct;11(5):719-25. doi: 10.1016/0301-5629(85)90105-x.
We have used spectral analysis of signals from a pulsed, range-gated Doppler ultrasonic instrument to make quantitative measurements of arterial blood flow velocity in the hands of normal subjects and persons with Raynaud's phenomenon. We measured the peak velocity during the cardiac cycle and the time integral of the velocity signal over the cardiac cycle. This latter parameter gives a sensitive indication of the degree of vasoconstriction in response to cold. Our preliminary results, based on findings in 13 subjects, suggest that Doppler ultrasound can differentiate persons with Raynaud's phenomenon from normal subjects.
我们使用了来自脉冲、距离选通多普勒超声仪器的信号频谱分析，对正常受试者和患有雷诺现象的人的手部动脉血流速度进行了定量测量。我们测量了心动周期中的峰值速度以及心动周期内速度信号的时间积分。后一个参数能灵敏地指示出对寒冷反应时血管收缩的程度。基于13名受试者的研究结果，我们的初步结果表明，多普勒超声能够区分患有雷诺现象的人和正常受试者。
