后生动物记忆的病毒档案库
A Viral (Arc)hive for Metazoan Memory.
机构信息
Section of Surgical Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
Department of Virus Research, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan; Department of Mammalian Regulatory Network, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
出版信息
Cell. 2018 Jan 11;172(1-2):8-10. doi: 10.1016/j.cell.2017.12.029.
Arc, a master regulator of synaptic plasticity, contains sequence elements that are evolutionarily related to retrotransposon Gag genes. Two related papers in this issue of Cell show that Arc retains retroviral-like capsid-forming ability and can transmit mRNA between cells in the nervous system, a process that may be important for synaptic function.
Arc，一种突触可塑性的主要调节因子，包含与逆转录病毒 Gag 基因在进化上相关的序列元件。本期《细胞》中的两篇相关论文表明，Arc 保留了逆转录病毒样衣壳形成能力，并能在神经系统的细胞间传递 mRNA，这一过程可能对突触功能很重要。
Zotero 插件