Klainbart Sigal, Chai Orit, Vaturi Rafael, Rapoport Kira, Aroch Itamar, Shamir Merav Hagar
Department of Small Animal Emergency and Critical Care, The Hebrew University Veterinary Teaching Hospital, Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel.
Department of Neurology, The Hebrew University Veterinary Teaching Hospital, Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel.
Vet Clin Pathol. 2018 Mar;47(1):138-141. doi: 10.1111/vcp.12560. Epub 2018 Jan 12.
Spinal spirocercosis due to aberrant Spirocerca lupi nematode migration is an emerging etiology for acute myelitis in dogs in Israel, causing severe, mostly nonsymmetrical hind limb paresis or paralysis, and sometimes tetraparesis or tetraparalysis. So far, incidental identification of parasites during spinal surgery or at necropsy provides the only definite diagnosis, while antemortem diagnosis of this condition has been uncertain. Specifically, antemortem diagnosis is based on the typical clinical presentation of acute, progressive, asymmetrical hind limb paresis or paralysis, with moderate to severe eosinophilic to mixed cerebrospinal fluid (CSF) pleocytosis and increased CSF protein concentration. Exclusion of other differential diagnoses also requires using spinal cord imaging. In this novel report, we document a case of an intradural spinal spirocercosis in a dog, diagnosed antemortem, by detecting S lupi eggs in the CSF, and subsequent treatment, resulting in the resolution of the clinical signs.
由异常迁移的狼旋尾线虫引起的脊髓旋尾丝虫病是以色列犬急性脊髓炎的一种新出现的病因，可导致严重的、大多不对称的后肢轻瘫或瘫痪，有时也会出现四肢轻瘫或四肢瘫痪。到目前为止，在脊髓手术或尸检期间偶然发现寄生虫是唯一明确的诊断方法，而生前诊断这种疾病一直不确定。具体而言，生前诊断基于急性、进行性、不对称后肢轻瘫或瘫痪的典型临床表现，伴有中度至重度嗜酸性粒细胞增多至混合性脑脊液（CSF）细胞增多以及CSF蛋白浓度升高。排除其他鉴别诊断还需要使用脊髓成像。在这份新颖的报告中，我们记录了一例犬硬膜内脊髓旋尾丝虫病病例，通过在脑脊液中检测到狼旋尾线虫卵进行生前诊断，并进行了后续治疗，临床症状得以缓解。
