听神经瘤对英国长期生活质量结果的影响。
The impact of acoustic neuroma on long-term quality-of-life outcomes in the United Kingdom.
作者信息
Lodder Wouter L, van der Laan Bernard F A M, Lesser Tristram H, Leong Samuel C
机构信息
Department of Otorhinolaryngology/Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Department of Otorhinolaryngology/Head and Neck Surgery, Medical Centre Leeuwarden, Leeuwarden, The Netherlands.
出版信息
Eur Arch Otorhinolaryngol. 2018 Mar;275(3):709-717. doi: 10.1007/s00405-018-4864-0. Epub 2018 Jan 12.
OBJECTIVE
To quantify the impact of acoustic neuroma on the quality-of-life (QOL) patients in the United Kingdom.
STUDY DESIGN
Online questionnaire survey.
PATIENTS
Members of the British Acoustic Neuroma Association received PANQOL questionnaires.
RESULTS
Of the 880 BANA members contacted, 397 (45.1%) responded, although only 359 had complete datasets for analysis. Composite QOL scores were as follows: for microsurgery 58 (SD 35), for radiotherapy 56 (SD18), for combination of surgery and radiotherapy 49 (SD 14), and for the observation group 54 (SD 20). No statistical significance with ANOVA (p = 0.532). Mean (SD) composite QOL scores were as follows: for follow-up < 6 52 (SD 18), for follow-up 6-10 55 (SD 20) and follow-up > 10 years 65 (SD 45). Overall, these values were significantly different compared by ANOVA (p < 0.001). Patients with facial paralysis showed no statistical significant differences between the different treatment groups.
CONCLUSIONS
Short- (< 6 years) and long-term (> 10 years) QOL outcomes show no significant differences between the different treatment groups.
目的
量化听神经瘤对英国患者生活质量（QOL）的影响。
研究设计
在线问卷调查。
患者
英国听神经瘤协会成员收到了PANQOL问卷。
结果
在联系的880名BANA成员中，397人（45.1%）做出了回应，不过只有359人有完整数据集可供分析。综合生活质量得分如下：显微手术为58（标准差35），放射治疗为56（标准差18），手术与放射治疗联合为49（标准差14），观察组为54（标准差20）。方差分析无统计学意义（p = 0.532）。平均（标准差）综合生活质量得分如下：随访<6年为52（标准差18），随访6 - 10年为55（标准差20），随访>10年为65（标准差45）。总体而言，方差分析显示这些值有显著差异（p < 0.001）。面瘫患者在不同治疗组之间无统计学显著差异。
结论
短期（<6年）和长期（>10年）生活质量结果在不同治疗组之间无显著差异。
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