伴有口腔受累的淀粉样变性。

Amyloidosis with oral involvement.

作者信息

Smith A, Speculand B

出版信息

Br J Oral Maxillofac Surg. 1985 Dec;23(6):435-44. doi: 10.1016/0266-4356(85)90028-2.

Abstract

Amyloidosis is a disease complex in which amyloid fibrils, formed from various serum proteins, may be deposited in a local or systemic distribution. When this deposition affects vital organs the disease usually is fatal because there is no effective treatment. This paper reports a case of amyloidosis with oral involvement and discusses recent advances concerning the properties of amyloid fibrils and the various pathogenic mechanisms responsible for their formation.

摘要

淀粉样变性是一种疾病综合征，其中由各种血清蛋白形成的淀粉样纤维可能以局部或全身分布的形式沉积。当这种沉积影响重要器官时，由于没有有效的治疗方法，该疾病通常是致命的。本文报告了一例伴有口腔受累的淀粉样变性病例，并讨论了有关淀粉样纤维特性及其形成的各种致病机制的最新进展。