新型双哌啶鎓化合物的抗菌活性
Antimicrobial Activities of Novel Bis-Piperidinium Compounds.
作者信息
Saif Muhammad Jawwad, Zuber Mohammed, Anwar Jamil, Munawar Munawar Ali
机构信息
Department of Applied Chemistry, Government College University, Pakistan.
Institute of Chemistry, University of the Punjab, Pakistan.
出版信息
Pol J Microbiol. 2012 Sep 28;61(3):223-225.
The antimicrobial activity of two new series of bis-piperidinium compounds with alkyl chains of different lengths against bacterial (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis) and fungal strains (Aspergillus flavus, Aspergillus niger, Rhodolorula rubera, Lipomyces lopofera and Candida albicans), are described. Antimicrobial activities of the synthesized compounds were compared to that of dodecyltrimethylammonium chloride. Bis-piperidinium salts possessing 12-16 carbon side chains showed better antimicrobial properties as compared to the standard dodecyltrimethylammonium chloride.
描述了两个新系列具有不同长度烷基链的双哌啶鎓化合物对细菌（大肠杆菌、铜绿假单胞菌、金黄色葡萄球菌和枯草芽孢杆菌）和真菌菌株（黄曲霉、黑曲霉、红酵母、洛泊费拉油脂酵母和白色念珠菌）的抗菌活性。将合成化合物的抗菌活性与十二烷基三甲基氯化铵的抗菌活性进行了比较。与标准的十二烷基三甲基氯化铵相比，具有12 - 16个碳侧链的双哌啶鎓盐表现出更好的抗菌性能。
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