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稳定型氟化亚锡牙膏的优势:一款针对患者偏好设计的先进配方产品。

The Case for Stabilized Stannous Fluoride Dentifrice: An Advanced Formulation Designed for Patient Preference.

作者信息

He Tao, Farrell Svetlana

机构信息

Procter & Gamble, Mason, OH, USA.

出版信息

J Clin Dent. 2017 Dec;28(4 Spec No B):B1-5.

PMID:29334434
Abstract

Oral diseases, particularly caries and gingivitis, continue to be widespread. Incorporating a stabilized stannous fluoride dentifrice into patients' daily oral hygiene routine is a convenient, cost effective approach to improve and protect their oral health and the appearance of their smile. Unlike other common fluorides that only provide anti-caries benefits (e.g., sodium fluoride and sodium monofluorophosphate), stabilized stannous fluoride formulations have demonstrated broader and significantly greater protection, also reducing plaque, gingivitis, erosion, sensitivity, and halitosis. To deliver the full range of benefits and simultaneously deliver whitening and tartar control benefits, stannous fluoride requires careful formulation. Procter & Gamble is the only dentifrice manufacturer with decades of patented innovations to overcome these formulation challenges, resulting in a large portfolio of stannous fluoride-containing dentifrice products marketed under the Crest® Pro-Health™ name that are available today. The most recent innovation is a "smooth texture" variant of Crest Pro-Health, containing stabilized stannous fluoride with zinc citrate as the anti-calculus agent. This product was developed to deliver a patient preferred brushing experience with the full range of benefits offered by Crest Pro-Health. This article discusses two common misconceptions about dentifrice, describes the history of key Crest stannous fluoride innovations, and outlines the research in this issue demonstrating health and cosmetic benefits of the new Crest Pro-Health smooth texture variant.

摘要

口腔疾病,尤其是龋齿和牙龈炎,仍然广泛存在。将含有稳定化氟化亚锡的牙膏纳入患者的日常口腔卫生习惯中,是一种方便且经济有效的方法,可改善和保护他们的口腔健康以及笑容外观。与其他仅具有防龋益处的常见氟化物(如氟化钠和单氟磷酸钠)不同,稳定化氟化亚锡配方已显示出更广泛且显著更强的保护作用,还能减少牙菌斑、牙龈炎、牙齿侵蚀、牙齿敏感和口臭。为了提供全方位的益处并同时实现美白和防牙石功效,氟化亚锡需要精心配制。宝洁公司是唯一一家拥有数十年专利创新成果以克服这些配方挑战的牙膏制造商,从而推出了大量以佳洁士®专业健康™品牌销售的含氟化亚锡牙膏产品,这些产品如今已面市。最新的创新产品是佳洁士专业健康系列的“丝滑质地”变体,含有稳定化氟化亚锡并以柠檬酸锌作为防牙石剂。开发该产品是为了让患者获得他们所偏爱的刷牙体验,并具备佳洁士专业健康系列所提供的全方位益处。本文讨论了关于牙膏的两个常见误解,描述了佳洁士关键氟化亚锡创新的历史,并概述了在这一问题上的研究,这些研究证明了新款佳洁士专业健康丝滑质地变体在健康和美容方面的益处。

相似文献

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The Case for Stabilized Stannous Fluoride Dentifrice: An Advanced Formulation Designed for Patient Preference.稳定型氟化亚锡牙膏的优势:一款针对患者偏好设计的先进配方产品。
J Clin Dent. 2017 Dec;28(4 Spec No B):B1-5.
2
In Vitro and In Vivo Evaluations of the Anticalculus Effect of a Novel Stabilized Stannous Fluoride Dentifrice.新型稳定氟化亚锡牙膏防结石效果的体外和体内评价
J Clin Dent. 2017 Dec;28(4):B21-26.
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The clinical effect of a stabilized stannous fluoride dentifrice on plaque formation, gingivitis and gingival bleeding: a six-month study.一种稳定的氟化亚锡牙膏对牙菌斑形成、牙龈炎和牙龈出血的临床效果:一项为期六个月的研究。
J Clin Dent. 1995;6 Spec No:54-8.
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Comparative investigation of the efficacy of triclosan/copolymer/sodium fluoride and stannous fluoride/sodium hexametaphosphate/zinc lactate dentifrices for the control of established supragingival plaque and gingivitis in a six-month clinical study.三氯生/共聚物/氟化钠与氟化亚锡/六偏磷酸钠/乳酸锌牙膏控制已形成的龈上菌斑和牙龈炎疗效的六个月临床比较研究。
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Assessment of the Effects of a Novel Stabilized Stannous Fluoride Dentifrice on Gingivitis in a Two-Month Positive-Controlled Clinical Study.在一项为期两个月的阳性对照临床研究中评估新型稳定氟化亚锡牙膏对牙龈炎的影响。
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Comparative Antiplaque Effect of Two Antimicrobial Dentifrices: Laboratory and Clinical Evaluations.两种抗菌牙膏的抗牙菌斑效果比较:实验室与临床评估
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A Randomized Clinical Trial to Measure the Erosion Protection Benefits of a Novel Stabilized Stannous Fluoride Dentifrice versus a Control Dentifrice.一项随机临床试验,旨在衡量新型稳定化氟化亚锡牙膏与对照牙膏相比的防龋益处。
J Clin Dent. 2017 Dec;28(4 Spec No B):B17-20.
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The comparative efficacy of stabilized stannous fluoride dentifrice, peroxide/baking soda dentifrice and essential oil mouthrinse for the prevention of gingivitis.稳定型氟化亚锡牙膏、过氧化物/小苏打牙膏和精油漱口水预防牙龈炎的比较疗效。
J Clin Dent. 1997;8(2 Spec No):46-53.
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A clinical investigation of the efficacy of three commercially available dentifrices for controlling established gingivitis and supragingival plaque.三种市售牙膏控制已患牙龈炎和龈上菌斑疗效的临床研究。
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A comparison of stabilized stannous fluoride dentifrice and triclosan/copolymer dentifrice for efficacy in the reduction of gingivitis and gingival bleeding: six-month clinical results.稳定型氟化亚锡牙膏与三氯生/共聚物牙膏在减少牙龈炎和牙龈出血方面的疗效比较:六个月临床结果
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Clin Exp Dent Res. 2024 Dec;10(6):e70020. doi: 10.1002/cre2.70020.
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Structural characterization of tin in toothpaste by dynamic nuclear polarization enhanced Sn solid-state NMR spectroscopy.通过动态核极化增强的锡固态核磁共振光谱对牙膏中锡的结构表征。
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Comparison of new formulas of stannous fluoride toothpastes with other commercially available fluoridated toothpastes: A systematic review and meta-analysis of randomised controlled trials.
比较不同品牌含氟牙膏的防龋效果:随机对照试验的系统评价和荟萃分析
Int Dent J. 2020 Dec;70(6):418-426. doi: 10.1111/idj.12588. Epub 2020 Jul 4.