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降低细菌在掺钛类金刚石碳涂层上的黏附

Reduction of bacterial adhesion on titanium-doped diamond-like carbon coatings.

作者信息

Zhao Ying-Yu, Zhao Buyun, Su Xueju, Zhang Shuai, Wang Su, Keatch Robert, Zhao Qi

机构信息

a Rehabilitation Medicine Department , the First Hospital of China Medical University , Shenyang , PR China.

b Medical Research Council Laboratory of Molecular Biology , University of Cambridge , Cambridge , UK.

出版信息

Biofouling. 2018 Jan;34(1):26-33. doi: 10.1080/08927014.2017.1403592.

DOI:10.1080/08927014.2017.1403592
PMID:29334813
Abstract

A range of titanium doped diamond-like carbon (Ti-DLC) coatings with different Ti contents were prepared on stainless steel substrates using a plasma-enhanced chemical vapour deposition technique. It was found that both the electron donor surface energy and the surface roughness of the Ti-DLC coatings increased with increasing Ti contents in the coatings. Bacterial adhesion to the coatings was evaluated against Escherichia coli WT F1693 and Pseudomonas aeruginosa ATCC 33347. The experimental data showed that bacterial adhesion decreased with the increases of the Ti content, the electron donor surface energy and surface roughness of the coatings, while the bacterial removal percentage increased with the increases of these parameters. The Ti-DLC coatings reduced bacterial attachment by up to 75% and increased bacterial detachment from 15 to 45%, compared with stainless steel control.

摘要

采用等离子体增强化学气相沉积技术,在不锈钢基底上制备了一系列钛含量不同的掺钛类金刚石碳(Ti-DLC)涂层。研究发现,Ti-DLC涂层的电子供体表面能和表面粗糙度均随涂层中钛含量的增加而增大。以大肠杆菌野生型F1693和铜绿假单胞菌ATCC 33347为对象,评估了细菌对涂层的粘附情况。实验数据表明,细菌粘附随涂层钛含量、电子供体表面能和表面粗糙度的增加而降低,而细菌去除率则随这些参数的增加而提高。与不锈钢对照相比,Ti-DLC涂层使细菌附着减少了75%,细菌脱离率从15%提高到了45%。

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