Zhu Jing-Jing, Meng Xiao, Zhang Chi, Bian Jie, Lu Zhenda, Liu Ying, Zhang Weihua
College of Engineering and Applied Sciences, National Laboratory of Solid State Microstructures and Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China.
Phys Chem Chem Phys. 2018 Jan 31;20(5):3424-3429. doi: 10.1039/c7cp07219h.
The surface-assisted laser desorption/ionization (SALDI) effect is investigated on Au plated anodized aluminum oxide (Au/AAO) thin films, a new type of low-cost broadband plasmonic absorber, which has attracted a lot of attention recently. Mass spectrometry (MS) measurements show that the ionization efficiency of Au/AAO substrates can be significantly improved (×30 fold) by simply tuning the size of nanopores in Au/AAOs. This leads to a signal-to-noise ratio of 394, which is 4 times better than the result obtained using the conventional matrix-assisted laser desorption/ionization (MALDI)-MS technique. Experimental and theoretical studies show that the dramatic improvement is caused by the pore-size-dependent optical and thermal properties of Au/AAOs. It provides a simple yet effective strategy for designing and building high performance plasmonic SALDI substrates.
在镀有金的阳极氧化铝（Au/AAO）薄膜上研究了表面辅助激光解吸/电离（SALDI）效应，Au/AAO薄膜是一种新型低成本宽带等离子体吸收器，最近受到了广泛关注。质谱（MS）测量表明，通过简单调整Au/AAO中纳米孔的尺寸，Au/AAO基底的电离效率可显著提高（30倍）。这导致信噪比达到394，比使用传统基质辅助激光解吸/电离（MALDI）-MS技术获得的结果要好4倍。实验和理论研究表明，这种显著的改进是由Au/AAO的孔径依赖性光学和热学性质引起的。它为设计和构建高性能等离子体SALDI基底提供了一种简单而有效的策略。
