Lermen Joice, Bernieri Tanandra, Rodrigues Isabel S, Suyenaga Edna S, Ardenghi Patrícia G
a Department of Health Sciences , Feevale University , Novo Hamburgo , Rio Grande do Sul (RS) , Brazil.
J Environ Sci Health B. 2018 Apr 3;53(4):215-221. doi: 10.1080/03601234.2017.1421823. Epub 2018 Jan 16.
This study aimed to evaluate the exposure to pesticides through the biomarkers analysis, as well as life habits and use of Personal Protective Equipment (PPE) in a group of farmers who grow citrus in the Vale do Caí region, in Rio Grande do Sul, southern Brazil. The study population consisted of 73 volunteer farmers, 45 males and 28 females, aged between 13 and 69 years old. The control group consisted of 30 individuals who were not exposed to pesticides. Measures of urea, creatinine, aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyltransferase (GGT), plasma cholinesterase (BChE) activity, and hematological parameters were analyzed. The study population also answered a structured questionnaire on life habits and health. The results showed that BChE activity was significantly lower in the exposed group than in the control group. AST, ALT, and creatinine were increased in the group of women exposed to pesticides when compared to the control group. GGT, urea, and hematological parameters did not show statistical differences for both male and female group. The most prevalent symptom reported by farmers after exposure to pesticides was headache. Furthermore, it was verified that the use of complete PPE is only made by 38% of the studied population.
本研究旨在通过生物标志物分析评估巴西南部南里奥格兰德州卡伊河谷地区一组种植柑橘的农民接触农药的情况，以及他们的生活习惯和个人防护装备（PPE）的使用情况。研究人群由73名志愿农民组成，其中45名男性和28名女性，年龄在13至69岁之间。对照组由30名未接触农药的个体组成。分析了尿素、肌酐、天冬氨酸转氨酶（AST）、丙氨酸转氨酶（ALT）、γ-谷氨酰转移酶（GGT）、血浆胆碱酯酶（BChE）活性和血液学参数。研究人群还回答了一份关于生活习惯和健康的结构化问卷。结果显示，接触组的BChE活性显著低于对照组。与对照组相比，接触农药的女性组的AST、ALT和肌酐有所升高。GGT、尿素和血液学参数在男性和女性组中均未显示出统计学差异。农民接触农药后报告的最普遍症状是头痛。此外，经核实，只有38%的研究人群使用了完整的个人防护装备。
