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Potential of real-time PCR threshold cycle (CT) to predict presence of free toxin and clinically relevant C. difficile infection (CDI) in patients with cancer: A reply.

作者信息

Wilmore Stephanie, Goldenberg Simon D

机构信息

Centre for Clinical Infection and Diagnostics Research (CIDR), King's College, London and Guy's & St Thomas' NHS Foundation Trust, London, UK.

Centre for Clinical Infection and Diagnostics Research (CIDR), King's College, London and Guy's & St Thomas' NHS Foundation Trust, London, UK.

出版信息

J Infect. 2018 Apr;76(4):424-426. doi: 10.1016/j.jinf.2018.01.001. Epub 2018 Jan 11.

DOI:10.1016/j.jinf.2018.01.001
PMID:29337036
Abstract
摘要

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引用本文的文献

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Antibiotics (Basel). 2022 Apr 26;11(5):576. doi: 10.3390/antibiotics11050576.
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Recommendations for the diagnosis and treatment of Clostridioides difficile infection: An official clinical practice guideline of the Spanish Society of Chemotherapy (SEQ), Spanish Society of Internal Medicine (SEMI) and the working group of Postoperative Infection of the Spanish Society of Anesthesia and Reanimation (SEDAR).艰难梭菌感染的诊断和治疗建议：西班牙化疗学会（SEQ）、西班牙内科学会（SEMI）和西班牙麻醉与复苏学会术后感染工作组（SEDAR）的官方临床实践指南。
Rev Esp Quimioter. 2020 Apr;33(2):151-175. doi: 10.37201/req/2065.2020. Epub 2020 Feb 20.
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Dual Reporting of Clostridioides difficile PCR and Predicted Toxin Result Based on PCR Cycle Threshold Reduces Treatment of Toxin-Negative Patients without Increases in Adverse Outcomes.基于 PCR 循环阈值的艰难梭菌 PCR 和预测毒素结果的双重报告可减少对毒素阴性患者的治疗，而不会增加不良结局。
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Ultrasensitive Detection of Clostridioides difficile Toxins in Stool by Use of Single-Molecule Counting Technology: Comparison with Detection of Free Toxin by Cell Culture Cytotoxicity Neutralization Assay.利用单分子计数技术检测粪便中的艰难梭菌毒素：与细胞培养细胞毒性中和试验检测游离毒素的比较。
J Clin Microbiol. 2019 Oct 23;57(11). doi: 10.1128/JCM.00719-19. Print 2019 Nov.
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Ultrasensitive Detection of Clostridium difficile Toxins Reveals Suboptimal Accuracy of Toxin Gene Cycle Thresholds for Toxin Predictions.超敏检测艰难梭菌毒素揭示毒素基因循环阈值对毒素预测的准确性欠佳。
J Clin Microbiol. 2019 May 24;57(6). doi: 10.1128/JCM.01885-18. Print 2019 Jun.
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Toxin B PCR Amplification Cycle Threshold Adds Little to Clinical Variables for Predicting Outcomes in Infection: a Retrospective Cohort Study.毒素 B PCR 扩增循环阈值对预测感染结局的临床变量没有什么帮助：一项回顾性队列研究。
J Clin Microbiol. 2019 Jan 30;57(2). doi: 10.1128/JCM.01125-18. Print 2019 Feb.