From the Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan.
Anesthesiology. 2018 Feb;128(2):272-282. doi: 10.1097/ALN.0000000000002023.
The authors hypothesized that a multiparameter intraoperative decision support system with real-time visualizations may improve processes of care and outcomes.
Electronic health record data were retrospectively compared over a 6-yr period across three groups: experimental cases, in which the decision support system was used for 75% or more of the case at sole discretion of the providers; parallel controls (system used 74% or less); and historical controls before system implementation. Inclusion criteria were adults under general anesthesia, advanced medical disease, case duration of 60 min or longer, and length of stay of two days or more. The process measures were avoidance of intraoperative hypotension, ventilator tidal volume greater than 10 ml/kg, and crystalloid administration (ml · kg · h). The secondary outcome measures were myocardial injury, acute kidney injury, mortality, length of hospital stay, and encounter charges.
A total of 26,769 patients were evaluated: 7,954 experimental cases, 10,933 parallel controls, and 7,882 historical controls. Comparing experimental cases to parallel controls with propensity score adjustment, the data demonstrated the following medians, interquartile ranges, and effect sizes: hypotension 1 (0 to 5) versus 1 (0 to 5) min, P < 0.001, beta = -0.19; crystalloid administration 5.88 ml · kg · h (4.18 to 8.18) versus 6.17 (4.32 to 8.79), P < 0.001, beta = -0.03; tidal volume greater than 10 ml/kg 28% versus 37%, P < 0.001, adjusted odds ratio 0.65 (0.53 to 0.80); encounter charges $65,770 ($41,237 to $123,869) versus $69,373 ($42,101 to $132,817), P < 0.001, beta = -0.003. The secondary clinical outcome measures were not significantly affected.
The use of an intraoperative decision support system was associated with improved process measures, but not postoperative clinical outcomes.
作者假设,具有实时可视化功能的多参数术中决策支持系统可以改善护理流程和结果。
回顾性比较了 6 年间三组电子健康记录数据:实验组,提供者自行决定使用该决策支持系统 75%或以上;平行对照组(系统使用 74%或以下);以及系统实施前的历史对照组。纳入标准为全身麻醉下的成年人、合并严重内科疾病、手术时间 60 分钟或以上、住院时间两天或以上。流程指标为避免术中低血压、呼吸机潮气量大于 10ml/kg 和晶体液输注量(ml·kg·h)。次要结局指标为心肌损伤、急性肾损伤、死亡率、住院时间和总费用。
共评估了 26769 例患者:7954 例实验组、10933 例平行对照组和 7882 例历史对照组。通过倾向评分调整比较实验组与平行对照组的数据,结果显示以下中位数、四分位距和效应量:低血压 1(0 至 5)分钟与 1(0 至 5)分钟,P<0.001,β=-0.19;晶体液输注量 5.88ml·kg·h(4.18 至 8.18)与 6.17(4.32 至 8.79),P<0.001,β=-0.03;潮气量大于 10ml/kg 28%与 37%,P<0.001,调整后的比值比为 0.65(0.53 至 0.80);总费用 65770 美元(41237 美元至 123869 美元)与 69373 美元(42101 美元至 132817 美元),P<0.001,β=-0.003。次要临床结局指标无显著影响。
术中决策支持系统的使用与改善流程指标相关,但与术后临床结局无关。