Institut für Pharmazeutische Biologie und Phytochemie (IPBP), University of Münster, PharmaCampus, Corrensstraße 48, D-48149 Münster, Germany.
Int J Mol Sci. 2018 Jan 16;19(1):264. doi: 10.3390/ijms19010264.
Natural products from plants have been used since ancestral times to treat a wide variety of diseases worldwide. Plants of the genus (Sage) have been reported to be used for the prevention and treatment of various diseases and ailments. In particular, some species have been used in traditional medicine to treat diseases caused by protozoan parasites of the genera , and and scientific studies have demonstrated the activity of various isolated constituents from these plants against these pathogens. The current review attempts to give a critical overview of published information about the antiprotozoal activity of species of the genus and their chemical constituents. It is meant to give a unified overview of these results in order to avoid repetitions caused, e.g., by limited access to some primary reports, and to stimulate further research to possibly facilitate the development of new molecular leads against protozoal neglected tropical diseases (NTDs) based on constituents.
植物来源的天然产物自古以来就在世界各地被用于治疗各种疾病。据报道，属（鼠尾草属）的植物被用于预防和治疗各种疾病和不适。特别是，一些 物种在传统医学中被用于治疗由 属、 属和 属原生动物寄生虫引起的疾病，科学研究已经证明了这些植物的各种分离成分对这些病原体的活性。目前的综述试图对有关该属物种的抗原生动物活性及其化学成分的已发表信息进行批判性概述。其目的是对这些结果进行统一概述，以避免由于例如对某些原始报告的访问受限而导致的重复，并激发进一步的研究，以便可能基于 成分促进针对被忽视的热带病（NTDs）的新型分子先导的开发。
