Kizil Ramazan, Dilek Banu, Şahin Ebru, Engin Onur, Soylu Ali Can, Akalin Elif, Alper Serap
Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Dokuz Eylul University , Izmir, Turkey .
Lymphat Res Biol. 2018 Jun;16(3):263-269. doi: 10.1089/lrb.2017.0018. Epub 2018 Jan 17.
In this randomized controlled study, we aimed to evaluate the effect of shoulder flexion exercise using continuous passive motion (CPM) on lymphedema during the treatment of breast cancer-related lymphedema (BCRL).
Thirty patients with BCRL were enrolled and completed the study. Fourteen patients were treated with complete decongestive therapy (CDT) and CPM in the intervention group, and 16 patients were treated with CDT alone (control group) for 15 sessions. The main outcome measures were included; the shoulder range of motion (ROM) assessed with a goniometer, limb volume difference measured using the water immersion method, function with the Disabilities of the Arm, Shoulder and Hand (DASH), and the quality of life using the Functional Assessment of Cancer Therapy for Breast Cancer (FACT-B4). Lymphedema volume measures were taken at baseline, on days 1, 2, 3, 4, 5, 10, and 15; and shoulder ROM, FACT-B4, and DASH were taken at baseline and on day 15.
All subjects were similar at baseline. After treatment significant improvement was found in ROM, volumetric differences, DASH, and FACT-B4 scores in both groups. No significant differences were observed in the volumetric differences, ROM, and the DASH, and FACT-B4 scores between the groups, except for the FACT-B4 physical well-being subscores, which were better in intervention group.
Our study results showed that CPM did not contribute to the reduction of BCRL.
在这项随机对照研究中，我们旨在评估在乳腺癌相关淋巴水肿（BCRL）治疗期间，使用持续被动运动（CPM）进行肩部屈曲运动对淋巴水肿的影响。
招募了30例BCRL患者并完成研究。干预组14例患者接受了完全消肿治疗（CDT）和CPM，16例患者仅接受CDT（对照组），共治疗15个疗程。主要观察指标包括：使用量角器评估的肩部活动范围（ROM）、采用水浸法测量的肢体体积差异、使用手臂、肩部和手部功能障碍（DASH）评估的功能以及使用乳腺癌治疗功能评估（FACT - B4）评估的生活质量。在基线、第1、2、3、4、5、10和15天测量淋巴水肿体积；在基线和第15天测量肩部ROM、FACT - B4和DASH。
所有受试者在基线时情况相似。治疗后，两组的ROM、体积差异、DASH和FACT - B4评分均有显著改善。除了FACT - B4生理健康子评分干预组更好外，两组之间在体积差异、ROM、DASH和FACT - B4评分方面未观察到显著差异。
我们的研究结果表明，CPM对减少BCRL没有作用。
