The complement system in the airway epithelium: An overlooked host defense mechanism and therapeutic target?
作者信息
Kulkarni Hrishikesh S, Liszewski M Kathryn, Brody Steven L, Atkinson John P
机构信息
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University in St Louis, St Louis, Mo; Division of Rheumatology, Department of Medicine, Washington University in St Louis, St Louis, Mo.
Division of Rheumatology, Department of Medicine, Washington University in St Louis, St Louis, Mo.
出版信息
J Allergy Clin Immunol. 2018 May;141(5):1582-1586.e1. doi: 10.1016/j.jaci.2017.11.046. Epub 2018 Jan 12.
Abstract
摘要
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本文引用的文献
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Production of complement components by cells of the immune system.免疫系统细胞产生补体成分。
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2
The Diacetyl-Exposed Human Airway Epithelial Secretome: New Insights into Flavoring-Induced Airways Disease.二乙酰暴露的人呼吸道上皮分泌组：对调味剂诱导的气道疾病的新见解。
Am J Respir Cell Mol Biol. 2017 Jun;56(6):784-795. doi: 10.1165/rcmb.2016-0372OC.
3
Complement: A primer for the coming therapeutic revolution.补体：即将到来的治疗革命入门。
Pharmacol Ther. 2017 Apr;172:63-72. doi: 10.1016/j.pharmthera.2016.11.014. Epub 2016 Dec 1.
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Complement component 7 (C7), a potential tumor suppressor, is correlated with tumor progression and prognosis.补体成分7（C7）是一种潜在的肿瘤抑制因子，与肿瘤进展和预后相关。
Oncotarget. 2016 Dec 27;7(52):86536-86546. doi: 10.18632/oncotarget.13294.
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The nasal mucosal late allergic reaction to grass pollen involves type 2 inflammation (IL-5 and IL-13), the inflammasome (IL-1β), and complement.鼻黏膜对草花粉的迟发型过敏反应涉及2型炎症（白细胞介素-5和白细胞介素-13）、炎症小体（白细胞介素-1β）和补体。
Mucosal Immunol. 2017 Mar;10(2):408-420. doi: 10.1038/mi.2016.74. Epub 2016 Sep 28.
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J Immunol. 2016 Apr 1;196(7):3159-67. doi: 10.4049/jimmunol.1502400. Epub 2016 Feb 29.
9
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10
Complement, a target for therapy in inflammatory and degenerative diseases.补体，炎症和退行性疾病的治疗靶点。
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