López Escárcega R, Gómez A, Beltrán U, Martínez W, Sandoval J, Seoane M, Lupi Herrera E
Arch Inst Cardiol Mex. 1985 Jul-Aug;55(4):343-7.
In order to assess the usefulness of blood samples taken from the right atrium (RA) in the calculation of intrapulmonary shunt (Qs/Qt), we correlated the values of Qs/Qt obtained through RA sampling with those obtained form a simultaneous sample of blood from the pulmonary artery (PA). The study was done in six mongrel dogs (15 to 23 Kg) who were anesthetized and artificially ventilated. The Qs/Qt measurements were repeated at different levels of cardiac output (CO). Changes in CO were elicited by both mechanical (A-V fistula) and pharmacological (Hydralazine) means. Besides the Qs/Qt correlation we also correlated the oxygen-hemoglobin saturation (Sat %) and oxygen tension (PvO2) values between the two sites of mixed venous sampling. The correlations of the different parameters between RA and PA samples we obtained were as follows: Qs/Qt r = 0.93 (p less than 0.001); Sat % r = 0.87 (p less than 0.001); and for PvO2 r = 0.91 (p less than 0.001). The significant correlations of these parameters were maintained independent of the CO level. We conclude that in our model a sample of blood obtained from the RA is useful for the calculation of Qs/Qt.
为了评估从右心房（RA）采集的血样在计算肺内分流（Qs/Qt）中的作用，我们将通过RA采样获得的Qs/Qt值与同时从肺动脉（PA）采集的血样所获得的Qs/Qt值进行了相关性分析。该研究在6只杂种犬（体重15至23千克）中进行，这些犬被麻醉并进行人工通气。在不同的心输出量（CO）水平下重复进行Qs/Qt测量。通过机械（动静脉瘘）和药理学（肼屈嗪）方法引起CO的变化。除了Qs/Qt相关性分析外，我们还对两个混合静脉采样部位之间的氧合血红蛋白饱和度（Sat%）和氧分压（PvO2）值进行了相关性分析。我们获得的RA和PA样本之间不同参数的相关性如下：Qs/Qt，r = 0.93（p < 0.001）；Sat%，r = 0.87（p < 0.001）；PvO2，r = 0.91（p < 0.001）。这些参数之间的显著相关性不受CO水平的影响。我们得出结论，在我们的模型中，从RA采集的血样可用于计算Qs/Qt。
