Rayn Kareem N, Hale Graham R, Grave Gustavo Pena-La, Agarwal Piyush K
Urologic Oncology Branch, National Cancer Institute, NIH, Bethesda, MD, USA.
Indian J Urol. 2018 Jan-Mar;34(1):11-19. doi: 10.4103/iju.IJU_296_17.
Nonmuscle invasive bladder cancer (NMIBC) remains a very challenging disease to treat with high rates of recurrence and progression associated with current therapies. Recent technological and biological advances have led to the development of novel agents in NMIBC therapy.
We reviewed existing literature as well as currently active and recently completed clinical trials in NMIBC by querying PubMed.gov and clinicaltrials.gov.
A wide variety of new therapies in NMIBC treatment are currently being developed, utilizing recent developments in the understanding of immune therapies and cancer biology.
The ongoing efforts to develop new therapeutic approaches for NMIBC look very promising and are continuing to evolve.
非肌肉浸润性膀胱癌(NMIBC)仍然是一种极具挑战性的疾病,当前治疗方法与之相关的复发率和进展率都很高。近期的技术和生物学进展已促使非肌肉浸润性膀胱癌治疗中新型药物的研发。
我们通过查询PubMed.gov和clinicaltrials.gov回顾了现有文献以及目前正在进行和最近完成的非肌肉浸润性膀胱癌临床试验。
目前正在利用免疫疗法和癌症生物学理解方面的最新进展,开发多种非肌肉浸润性膀胱癌的新疗法。
为非肌肉浸润性膀胱癌开发新治疗方法的持续努力看起来非常有前景,并且仍在不断发展。