Brown T D, Gabel R H, Pedersen D R, Bell L D, Blair W F
J Biomech. 1985;18(12):927-38. doi: 10.1016/0021-9290(85)90036-3.
For the purpose of improving accuracy of noninvasive flow measurements in small (1-2 mm diameter) blood vessels, an existing 20 MHz pulsed ultrasound Doppler velocimeter (PUDVM) has been augmented to allow fast Fourier transformation (FFT) of its Doppler shift signal. The modified instrument was used to collect velocity spectra for a benchtop test section delivering precise Poiseuille flows at velocities in the range of physiological interest. The velocity spectra demonstrated a substantial degree of broadening, much of which was attributable to the geometry of the finite sample volume size. Several spectral indices were studied as a function of flow field variables. Results showed that the intensity-weighted mean Doppler shift frequency, when converted to its corresponding velocity vM, agreed very closely with the theoretically predicted local fluid velocity. Measurement linearity and repeatability were evaluated for a number of system variables, indicating that FFT performance was essentially unaffected by several parameters capable of causing major degradation of (phasic) Doppler shift signals produced by conventional zero-crossing-counter circuitry. As presently configured, the augmented PUDVM instrument is fully capable of detailed flow field mapping in small subcutaneous vessels such as human digital arteries.
为提高对小直径(1 - 2毫米)血管无创血流测量的准确性,对现有的20兆赫脉冲超声多普勒测速仪(PUDVM)进行了改进,使其能够对多普勒频移信号进行快速傅里叶变换(FFT)。改进后的仪器用于为一个台式测试段采集速度谱,该测试段能以生理相关速度提供精确的泊肃叶流。速度谱显示出显著的展宽,其中大部分可归因于有限样本体积大小的几何形状。研究了几个谱指数作为流场变量的函数。结果表明,强度加权平均多普勒频移频率在转换为相应速度vM后,与理论预测的局部流体速度非常接近。对多个系统变量评估了测量线性度和重复性,表明FFT性能基本上不受几个能够导致传统过零计数器电路产生的(相位)多普勒频移信号严重退化的参数影响。按目前配置,改进后的PUDVM仪器完全能够对人体指动脉等皮下小血管进行详细的流场测绘。