Wells Rachel, Spurrier Andrew J, Linz Dominik, Gallagher Celine, Mahajan Rajiv, Sanders Prashanthan, Page Amanda, Lau Dennis H
Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute, University of Adelaide and Departments of Cardiology and Medicine, Royal Adelaide Hospital.
Department of Medicine, Royal Adelaide Hospital.
Vasc Health Risk Manag. 2017 Dec 29;14:1-11. doi: 10.2147/VHRM.S127393. eCollection 2018.
Postural tachycardia syndrome (POTS) is the combination of an exaggerated heart rate response to standing, in association with symptoms of lightheadedness or pre-syncope that improve when recumbent. The condition is often associated with fatigue and brain fog, resulting in significant disruptions at a critical time of diagnosis in adolescence and young adulthood. The heterogeneity of the underlying pathophysiology and the variable response to therapeutic interventions make management of this condition challenging for both patients and physicians alike. Here, we aim to review the factors and mechanisms that may contribute to the symptoms and signs of POTS and to present our perspectives on the clinical approach toward the diagnosis and management of this complex syndrome.
体位性心动过速综合征（POTS）是指站立时心率反应过度，并伴有头晕或接近晕厥的症状，而卧位时症状会改善。这种疾病常与疲劳和脑雾有关，在青少年和青年成年期的关键诊断阶段会导致严重干扰。潜在病理生理学的异质性以及对治疗干预的可变反应，使得患者和医生对这种疾病的管理都具有挑战性。在此，我们旨在回顾可能导致POTS症状和体征的因素及机制，并就这种复杂综合征的诊断和管理的临床方法提出我们的观点。
