Fite Laura Paul, Cohen Philip R
Dr. Fite is with Shenandoah Dermatology in Staunton, Virginia.
Dr. Cohen is with the Department of Dermatology at University of California San Diego in La Jolla, California.
J Clin Aesthet Dermatol. 2017 Sep;10(9):30-35. Epub 2017 Sep 1.
Polycystic ovarian syndrome is a common endocrine disorder with a variety of dermatologic manifestations among young women. Confluent and reticulated papillomatosis is a rare dermatosis of unknown etiology that is seldom reported in patients with polycystic ovarian syndrome. We describe the case of a young woman with obesity, confluent and reticulated papillomatosis, and concurrent acanthosis nigricans. Her history, physical examination, and laboratory evaluation led to the diagnosis of polycystic ovarian syndrome. The proposed etiologies and the various of treatment options for confluent and reticulated papillomatosis are discussed. In our case, the patient had a dramatic response to treatment with azithromycin. The etiology of confluent and reticulated papillomatosis remains to be established. Additionally, the mechanism behind the success of treatment with antibiotics is unclear; however, in this patient, azithromycin was a safe and effective option for the treatment of confluent and reticulated papillomatosis.
多囊卵巢综合征是一种常见的内分泌紊乱疾病，在年轻女性中伴有多种皮肤表现。融合性网状乳头瘤病是一种病因不明的罕见皮肤病，在多囊卵巢综合征患者中很少报道。我们描述了一名患有肥胖症、融合性网状乳头瘤病并同时伴有黑棘皮病的年轻女性病例。她的病史、体格检查和实验室检查结果确诊为多囊卵巢综合征。本文讨论了融合性网状乳头瘤病的推测病因及各种治疗选择。在我们的病例中，患者使用阿奇霉素治疗后反应显著。融合性网状乳头瘤病的病因仍有待确定。此外，抗生素治疗成功背后的机制尚不清楚；然而，对该患者而言，阿奇霉素是治疗融合性网状乳头瘤病的一种安全有效的选择。
