Basu Pallavi, Cohen Philip R
Dermatology, University of California, San Diego, USA.
Dermatology, San Diego Family Dermatology, San Diego, USA.
Cureus. 2019 Jan 25;11(1):e3956. doi: 10.7759/cureus.3956.
Polycystic ovarian syndrome is an endocrine disorder diagnosed commonly in young women. Various cutaneous manifestations can include acanthosis nigricans, acne, hirsutism, and alopecia. Confluent and reticulated papillomatosis is a rare skin condition that may be associated with polycystic ovarian syndrome. The etiology of confluent and reticulated papillomatosis is not yet well established but multiple theories exist regarding its pathogenesis. We describe a woman with established polycystic ovarian syndrome who presented with confluent and reticulated papillomatosis; her skin condition was successfully treated with azithromycin. The clinical features, differential diagnosis, epidemiology, and proposed etiologies for confluent and reticulated papillomatosis are discussed as well as possible treatment options. Among women with polycystic ovarian syndrome, confluent and reticulated papillomatosis and acanthosis nigricans can occur concurrently. Additionally, it is possible that confluent and reticulated papillomatosis occurs more commonly in this patient population.
多囊卵巢综合征是一种常见于年轻女性的内分泌紊乱疾病。各种皮肤表现可包括黑棘皮病、痤疮、多毛症和脱发。融合性网状乳头瘤病是一种罕见的皮肤疾病，可能与多囊卵巢综合征有关。融合性网状乳头瘤病的病因尚未完全明确，但关于其发病机制存在多种理论。我们描述了一位患有确诊多囊卵巢综合征且伴有融合性网状乳头瘤病的女性；她的皮肤疾病通过阿奇霉素成功治愈。文中讨论了融合性网状乳头瘤病的临床特征、鉴别诊断、流行病学、推测病因以及可能的治疗选择。在患有多囊卵巢综合征的女性中，融合性网状乳头瘤病和黑棘皮病可能同时出现。此外，融合性网状乳头瘤病在该患者群体中可能更常见。
