酷似恶性黑色素瘤的泪阜嗜酸性细胞瘤
Caruncular Oncocytoma Mimicking Malignant Melanoma.
作者信息
Surakiatchanukul Thamolwan, Sioufi Kareem, Pointdujour-Lim Renelle, Eagle Ralph C, Shields Jerry A, Shields Carol L
机构信息
Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Department of Ophthalmic Pathology, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
出版信息
Ocul Oncol Pathol. 2017 Nov;3(4):320-323. doi: 10.1159/000468524. Epub 2017 May 6.
PURPOSE
To report a case of pigmented caruncular oncocytoma that simulated malignant melanoma and discuss the associated ultrasonographic and pathologic features.
METHOD
Case report.
RESULTS
An 81-year-old female presented with a painless caruncular mass with a smooth brown surface suspicious for melanoma. Ultrasound biomicroscopy revealed a round mass with a large central cavity, more suggestive of a cystic rather than solid lesion. Following complete surgical resection, histopathology revealed a cystadenomatous lesion composed of bland cells with copious eosinophilic cytoplasm consistent with oncocytoma that had a central blood-filled cavity.
CONCLUSIONS
Oncocytoma is a benign tumor that can appear pigmented clinically and resemble melanoma. The definitive diagnosis requires histopathologic evaluation. Oncocytoma should be considered in the differential diagnosis of a pigmented caruncular mass.
目的
报告一例色素沉着性泪阜嗜酸性细胞瘤，其临床表现类似恶性黑色素瘤，并探讨相关的超声及病理特征。
方法
病例报告。
结果
一名81岁女性患者，泪阜出现无痛性肿物，表面光滑呈褐色，怀疑为黑色素瘤。超声生物显微镜检查显示为圆形肿物，中央有一个大腔，更提示为囊性而非实性病变。完整手术切除后，组织病理学显示为囊腺瘤性病变，由细胞温和、富含嗜酸性细胞质的细胞组成，符合嗜酸性细胞瘤，且中央有充满血液的腔。
结论
嗜酸性细胞瘤是一种良性肿瘤，临床上可表现为色素沉着，类似黑色素瘤。明确诊断需要组织病理学评估。在色素沉着性泪阜肿物的鉴别诊断中应考虑嗜酸性细胞瘤。
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