Department of Ophthalmology, Soroka University Medical Centre, Beer-Sheva, Israel.
Eye (Lond). 2009 May;23(5):1004-18. doi: 10.1038/eye.2008.316. Epub 2008 Oct 17.
Lesions of the caruncle are uncommon. On account of the histological composition of the caruncle, which includes, in addition to conjunctiva, hair follicles, sebaceous glands, sweat glands, and accessory lacrimal tissue, the caruncle may develop lesions that may be similar to those found in the skin, conjunctiva, or lacrimal gland. Clinical preoperative diagnosis is very difficult and reached only in about half of the cases. The vast majority of lesions of the caruncle are benign, mainly nevi. Reported malignant lesions are very rare but can be potentially fatal. Although malignancy is clinically overestimated, any suspected malignant lesion should be excised and examined histopathologically by an experienced pathologist. This study presents the clinical and histological data of 42 consecutive caruncular lesions processed at our laboratory and reviews previously reported cases of caruncular lesions.
结膜痣并不常见。由于结膜痣的组织学组成包括除了结膜外，还有毛囊、皮脂腺、汗腺和附属泪器组织，因此结膜痣可能会发展出与皮肤、结膜或泪腺相似的病变。术前临床诊断非常困难，只有大约一半的病例能够做出诊断。绝大多数结膜痣是良性的，主要是痣。报道的恶性病变非常罕见，但可能是致命的。尽管临床上对恶性病变的估计过高，但任何可疑的恶性病变都应切除，并由经验丰富的病理学家进行组织病理学检查。本研究介绍了在我们实验室处理的 42 例连续结膜痣的临床和组织学数据，并回顾了以前报道的结膜痣病例。
