Research Institute of Applied Chemistry, Shanxi University, Taiyuan, China.
Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Key Laboratory of Materials for Energy Conversion and Storage of Shanxi Province, Institute of Molecular Science, Shanxi University, Taiyuan, China.
Curr Med Chem. 2019;26(21):4003-4028. doi: 10.2174/0929867325666180117095528.
In recent years, aldehyde-appended fluorescence probes have attracted increasing attention. Fluorescent biological imaging includes many modern applications for cell and tissue imaging in biomedical research. Meanwhile, the nucleophilic mechanism is a very simple and convenient procedure for the preparation of aldehyde-sensing probes. This tutorial review focuses on aldehyde-bearing chemosensors based on nucleophilic addition mechanism with biological applications.
近年来，含醛基的荧光探针受到了越来越多的关注。荧光生物成像包括许多现代的细胞和组织成像在生物医学研究中的应用。同时，亲核机制是制备醛传感探针的一种非常简单方便的方法。本综述主要讨论了基于亲核加成机制的含醛基化学传感器及其在生物方面的应用。
