• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Serious Fall Injury History and Adverse Health Outcomes After Initiating Hemodialysis Among Older U.S. Adults.美国老年成年人开始血液透析后严重跌倒损伤史与不良健康结局。
J Gerontol A Biol Sci Med Sci. 2018 Aug 10;73(9):1216-1221. doi: 10.1093/gerona/glx260.
2
Serious Fall Injuries Before and After Initiation of Hemodialysis Among Older ESRD Patients in the United States: A Retrospective Cohort Study.美国老年终末期肾病患者血液透析前后严重跌倒损伤的回顾性队列研究。
Am J Kidney Dis. 2017 Jul;70(1):76-83. doi: 10.1053/j.ajkd.2016.11.021. Epub 2017 Jan 27.
3
Association of Serious Fall Injuries among United States End Stage Kidney Disease Patients with Access to Kidney Transplantation.美国终末期肾病患者接受肾移植与严重跌倒损伤的关联。
Clin J Am Soc Nephrol. 2018 Apr 6;13(4):628-637. doi: 10.2215/CJN.10330917. Epub 2018 Mar 6.
4
Association of Nondisease-Specific Problems with Mortality, Long-Term Care, and Functional Impairment among Older Adults Who Require Skilled Nursing Care after Dialysis Initiation.透析开始后需要专业护理的老年人中,非疾病特异性问题与死亡率、长期护理和功能障碍的关联。
Clin J Am Soc Nephrol. 2016 Dec 7;11(12):2218-2224. doi: 10.2215/CJN.01260216. Epub 2016 Oct 12.
5
Association of Reduced eGFR and Albuminuria with Serious Fall Injuries among Older Adults.老年人中估算肾小球滤过率降低及蛋白尿与严重跌倒损伤的关联
Clin J Am Soc Nephrol. 2016 Jul 7;11(7):1236-1243. doi: 10.2215/CJN.11111015. Epub 2016 Apr 18.
6
Recent History of Serious Fall Injuries and Posttransplant Outcomes Among US Kidney Transplant Recipients.美国肾移植受者近期严重跌倒损伤史和移植后结局。
Transplantation. 2019 May;103(5):1043-1050. doi: 10.1097/TP.0000000000002463.
7
Blood Pressure, Antihypertensive Polypharmacy, Frailty, and Risk for Serious Fall Injuries Among Older Treated Adults With Hypertension.老年高血压患者的血压、联合使用抗高血压药物、身体虚弱及严重跌倒受伤风险
Hypertension. 2017 Aug;70(2):259-266. doi: 10.1161/HYPERTENSIONAHA.116.09390. Epub 2017 Jun 26.
8
Acute Kidney Injury before Dialysis Initiation Predicts Adverse Outcomes in Hemodialysis Patients.透析前急性肾损伤预测血液透析患者的不良结局。
Am J Nephrol. 2018;47(6):427-434. doi: 10.1159/000489949. Epub 2018 Jun 7.
9
Risk of Dementia Diagnosis After Injurious Falls in Older Adults.老年人受伤性跌倒后痴呆诊断的风险。
JAMA Netw Open. 2024 Sep 3;7(9):e2436606. doi: 10.1001/jamanetworkopen.2024.36606.
10
Antihypertensive medications and serious fall injuries in a nationally representative sample of older adults.降压药物与老年人群中具有代表性的严重跌倒损伤。
JAMA Intern Med. 2014 Apr;174(4):588-95. doi: 10.1001/jamainternmed.2013.14764.

引用本文的文献

1
Development of a prognostic risk score to predict early mortality in incident elderly Japanese hemodialysis patients.建立预测日本老年血液透析患者早期死亡率的预后风险评分模型。
PLoS One. 2024 Apr 11;19(4):e0302101. doi: 10.1371/journal.pone.0302101. eCollection 2024.
2
Walking aids and complicated orthopedic diseases are risk factors for falls in hemodialysis patients: an observational study.助行器和复杂的骨科疾病是血液透析患者跌倒的危险因素:一项观察性研究。
BMC Geriatr. 2023 May 22;23(1):319. doi: 10.1186/s12877-023-04015-9.
3
Dialysis or kidney transplantation in older adults? A systematic review summarizing functional, psychological, and quality of life-related outcomes after start of kidney replacement therapy.老年人应选择透析还是肾移植?一项系统综述总结了肾脏替代治疗开始后的功能、心理及生活质量相关结局。
Int Urol Nephrol. 2022 Nov;54(11):2891-2900. doi: 10.1007/s11255-022-03208-2. Epub 2022 May 6.
4
The Impact of Falls: A Qualitative Study of the Experiences of People Receiving Haemodialysis.跌倒的影响:接受血液透析人群的经历的定性研究。
Int J Environ Res Public Health. 2022 Mar 24;19(7):3873. doi: 10.3390/ijerph19073873.
5
Chronic kidney disease as a risk factor for peripheral nerve impairment in older adults: A longitudinal analysis of Health, Aging and Body Composition (Health ABC) study.慢性肾脏病是老年人周围神经损伤的危险因素:健康、老龄化和身体成分(Health ABC)研究的纵向分析。
PLoS One. 2020 Dec 15;15(12):e0242406. doi: 10.1371/journal.pone.0242406. eCollection 2020.
6
Risk factors for mortality in elderly haemodialysis patients: a systematic review and meta-analysis.老年血液透析患者死亡的危险因素:系统评价和荟萃分析。
BMC Nephrol. 2020 Aug 31;21(1):377. doi: 10.1186/s12882-020-02026-x.
7
Mobility Impairment in Patients New to Dialysis.新透析患者的活动障碍。
Am J Nephrol. 2020;51(9):705-714. doi: 10.1159/000509225. Epub 2020 Aug 11.
8
Higher Amounts of Opioids Filled After Surgery Increase Risk of Serious Falls and Fall-Related Injuries Among Older Adults.手术后开处的阿片类药物剂量越高,老年人发生严重跌倒和跌倒相关伤害的风险就越高。
J Gen Intern Med. 2020 Oct;35(10):2917-2924. doi: 10.1007/s11606-020-06015-6. Epub 2020 Aug 3.
9
Skeletal muscle fibrosis is associated with decreased muscle inflammation and weakness in patients with chronic kidney disease.骨骼肌纤维化与慢性肾脏病患者的肌肉炎症和无力减轻有关。
Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1658-F1669. doi: 10.1152/ajprenal.00314.2018. Epub 2018 Oct 3.

本文引用的文献

1
Serious Fall Injuries Before and After Initiation of Hemodialysis Among Older ESRD Patients in the United States: A Retrospective Cohort Study.美国老年终末期肾病患者血液透析前后严重跌倒损伤的回顾性队列研究。
Am J Kidney Dis. 2017 Jul;70(1):76-83. doi: 10.1053/j.ajkd.2016.11.021. Epub 2017 Jan 27.
2
Association of Nondisease-Specific Problems with Mortality, Long-Term Care, and Functional Impairment among Older Adults Who Require Skilled Nursing Care after Dialysis Initiation.透析开始后需要专业护理的老年人中,非疾病特异性问题与死亡率、长期护理和功能障碍的关联。
Clin J Am Soc Nephrol. 2016 Dec 7;11(12):2218-2224. doi: 10.2215/CJN.01260216. Epub 2016 Oct 12.
3
Incorporating Geriatric Assessment into a Nephrology Clinic: Preliminary Data from Two Models of Care.将老年评估纳入肾脏病诊所:两种护理模式的初步数据。
J Am Geriatr Soc. 2016 Oct;64(10):2154-2158. doi: 10.1111/jgs.14262. Epub 2016 Jul 5.
4
Short-Term Risk of Serious Fall Injuries in Older Adults Initiating and Intensifying Treatment With Antihypertensive Medication.开始和强化使用抗高血压药物治疗的老年人发生严重跌倒损伤的短期风险。
Circ Cardiovasc Qual Outcomes. 2016 May;9(3):222-9. doi: 10.1161/CIRCOUTCOMES.115.002524. Epub 2016 May 10.
5
Association of Reduced eGFR and Albuminuria with Serious Fall Injuries among Older Adults.老年人中估算肾小球滤过率降低及蛋白尿与严重跌倒损伤的关联
Clin J Am Soc Nephrol. 2016 Jul 7;11(7):1236-1243. doi: 10.2215/CJN.11111015. Epub 2016 Apr 18.
6
Falls among hemodialysis patients: potential opportunities for prevention?血液透析患者跌倒:预防的潜在机会?
Clin Kidney J. 2014 Jun;7(3):257-63. doi: 10.1093/ckj/sfu034. Epub 2014 Apr 15.
7
Nondisease-specific problems and all-cause mortality among older adults with CKD: the REGARDS Study.慢性肾脏病老年患者的非疾病特异性问题及全因死亡率:REGARDS研究
Clin J Am Soc Nephrol. 2014 Oct 7;9(10):1737-45. doi: 10.2215/CJN.00880114. Epub 2014 Oct 2.
8
Antihypertensive medications and serious fall injuries in a nationally representative sample of older adults.降压药物与老年人群中具有代表性的严重跌倒损伤。
JAMA Intern Med. 2014 Apr;174(4):588-95. doi: 10.1001/jamainternmed.2013.14764.
9
Prognostic stratification in older adults commencing dialysis.老年起始透析患者的预后分层。
J Gerontol A Biol Sci Med Sci. 2014 Aug;69(8):1033-9. doi: 10.1093/gerona/glt289. Epub 2014 Jan 30.
10
The course of disability before and after a serious fall injury.严重跌倒损伤前后的残疾病程。
JAMA Intern Med. 2013 Oct 28;173(19):1780-6. doi: 10.1001/jamainternmed.2013.9063.

美国老年成年人开始血液透析后严重跌倒损伤史与不良健康结局。

Serious Fall Injury History and Adverse Health Outcomes After Initiating Hemodialysis Among Older U.S. Adults.

机构信息

Durham Veterans Affairs Geriatric Research Education and Clinical Center, Durham Veterans Affairs Medical Center (VAMC), North Carolina.

Divison of Geriatric Medicine, Department of Medicine, Duke University, Durham, North Carolina.

出版信息

J Gerontol A Biol Sci Med Sci. 2018 Aug 10;73(9):1216-1221. doi: 10.1093/gerona/glx260.

DOI:10.1093/gerona/glx260
PMID:29346522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7190925/
Abstract

BACKGROUND

Although older adults with predialysis chronic kidney disease are at higher risk for falls, the prognostic significance of a serious fall injury prior to dialysis initiation has not been well described in the end-stage renal disease population.

METHODS

We examined the association between a serious fall injury in the year prior to starting hemodialysis and adverse health outcomes in the year following dialysis initiation using a retrospective cohort study of U.S. Medicare beneficiaries ≥ 67 years old who initiated dialysis in 2010-2012. Serious fall injuries were defined using diagnostic codes for falls plus an injury (fracture, joint dislocation, or head injury). Health outcomes, defined as time-to-event variables within the first year of dialysis, included four outcomes: a subsequent serious fall injury, hospital admission, post-acute skilled nursing facility (SNF) utilization, and mortality.

RESULTS

Among this cohort of 81,653 initiating hemodialysis, 2,958 (3.6%) patients had a serious fall injury in the year prior to hemodialysis initiation. In the first year of dialysis, 7.6% had a subsequent serious fall injury, 67.6% a hospitalization, 30.7% a SNF claim, and 26.1% died. Those with versus without a serious fall injury in the year prior to hemodialysis initiation were at higher risk (hazard ratio, 95% confidence interval) for a subsequent serious fall injury (2.65, 2.41-2.91), hospitalization (1.11, 1.06-1.16), SNF claim (1.40, 1.30-1.50), and death (1.14, 1.06-1.22).

CONCLUSIONS

For older adults initiating dialysis, a history of a serious fall injury may provide prognostic information to support decision making and establish expectations for life after dialysis initiation.

摘要

背景

尽管透析前慢性肾脏病的老年患者发生跌倒的风险更高,但在终末期肾病患者中,透析前一年内发生严重跌倒损伤对预后的影响尚未得到充分描述。

方法

我们使用美国 Medicare 受益人的回顾性队列研究,对 2010-2012 年期间开始透析的≥67 岁患者进行了研究,调查了在开始血液透析前一年发生严重跌倒损伤与透析后一年内不良健康结局之间的关系。严重跌倒损伤是通过跌倒加损伤的诊断代码(骨折、关节脱位或头部损伤)来定义的。健康结局是指在透析的第一年中作为时间相关变量的四个结局:随后发生严重跌倒损伤、住院、急性后康复护理机构(SNF)利用和死亡。

结果

在这个接受血液透析的 81653 例队列中,2958 例(3.6%)患者在开始血液透析前一年发生了严重的跌倒损伤。在透析的第一年中,7.6%的患者随后发生了严重跌倒损伤,67.6%的患者住院,30.7%的患者入住 SNF,26.1%的患者死亡。与透析前一年没有严重跌倒损伤的患者相比,这些患者发生随后的严重跌倒损伤(危险比,95%置信区间)、住院(1.11,1.06-1.16)、入住 SNF(1.40,1.30-1.50)和死亡(1.14,1.06-1.22)的风险更高。

结论

对于开始透析的老年患者,严重跌倒损伤的病史可能提供预后信息,以支持决策并为透析后生活建立预期。